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Details

Stereochemistry ACHIRAL
Molecular Formula Pb
Molecular Weight 207.2
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEAD

SMILES

[Pb]

InChI

InChIKey=FOSOXHMVHOGFCF-UHFFFAOYSA-N
InChI=1S/Pb.2H

HIDE SMILES / InChI

Molecular Formula Pb
Molecular Weight 207.2
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Lead(II) acetate is a white crystalline chemical compound with a sweetish taste. Lead(II) acetate is used as a mordant in textile printing and dyeing, as a drier in paints and varnishes, and in preparing other lead compounds. It was historically used as a sweetener and for cosmetics.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Chromosomal effects of lead: A critical review.
1980
Clastogenicity evaluation of seven chemicals commonly found at hazardous industrial waste sites.
1989 Dec
Scope and mechanism of intramolecular aziridination of cyclopent-3-enyl-methylamines to 1-azatricyclo[2.2.1.0(2,6)]heptanes with lead tetraacetate.
2009 Aug 26
Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing.
2011 Mar
A review of selected chemical additives in cosmetic products.
2014 Nov-Dec
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
It was examined the associations of increased glial fibrillary acidic protein (GFAP) levels and hypertrophie changes with susceptibility to toxic insult in C6 rat glioma cells. The cells were treated with serial pulses of dibutyryl-cAMP (dBcAMP) (each 48 hr) which increased levels of GFAP approximately twofold and the surface to volume ratio by approximately 1.7 times after the third pulse. This treatment reduced cell number by 22% and increased total protein by 10%. The cells were then exposed to different toxic substances [tin chloride, lead tetraacetate, chloroquine, cadmium chloride, aluminium chloride, mercuric chloride, acrylamide, triethyltin bromide, ethylenediaminetetraacetatic acid (EDTA)] and toxicity to the cells measured by the neutral red (NR) assay. With the exceptions of aluminium chloride and EDTA, 50% effective concentration (EC(50)) values for the toxic substances were increased up to 10,000 times (for cadmium chloride).
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:09:02 UTC 2023
Edited
by admin
on Fri Dec 15 16:09:02 UTC 2023
Record UNII
2P299V784P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEAD
HSDB   MART.   MI   WHO-DD  
Systematic Name English
METALLIC LEAD
Common Name English
LEAD POWDER
Common Name English
LEAD ELEMENT
Common Name English
LEAD FLAKE
Common Name English
LEAD [IARC]
Common Name English
PLUMBUM METALLICUM
HPUS  
Common Name English
PLUMBUM METALLICUM [HPUS]
Common Name English
Lead [WHO-DD]
Common Name English
C.I. 77575
Code English
LEAD [HSDB]
Common Name English
LEAD METAL
Common Name English
LEAD [MI]
Common Name English
LEAD [MART.]
Common Name English
C.I. PIGMENT METAL 4
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C45383
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
CFR 21 CFR 862.3550
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
NCI_THESAURUS C637
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
Code System Code Type Description
MERCK INDEX
m6721
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY Merck Index
SMS_ID
100000126012
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
CHEBI
27889
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
FDA UNII
2P299V784P
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
CAS
7439-92-1
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
PUBCHEM
5352425
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
MESH
D007854
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
EVMPD
SUB33106
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
RXCUI
6260
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID2024161
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
WIKIPEDIA
Lead
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
ECHA (EC/EINECS)
231-100-4
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
NCI_THESAURUS
C44396
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
HSDB
231
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
CHEBI
25016
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
DAILYMED
2P299V784P
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
EVMPD
SUB88433
Created by admin on Fri Dec 15 16:09:02 UTC 2023 , Edited by admin on Fri Dec 15 16:09:02 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
LEAD (ng/cigarette) Canadian = 257.7 SD(77.7) Imported = 257.0 SD(66.5)
Related Record Type Details
PARENT -> IMPURITY
IMPURITY -> PARENT
Related Record Type Details
ACTIVE MOIETY