LECONOTIDE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20002322 | https://www.thepharmaletter.com/article/leconotide-s-potential-for-non-opioid-pain-relief | https://www.ncbi.nlm.nih.gov/pubmed/21539704

LECONOTIDE is an omega-conotoxin peptide with analgesic properties blocking neuronal voltage-sensitive calcium channels. It was under investigation for the treatment of pain conditions.

Originator

Approval Year

PubMed

Title	Date	PubMed
CNSB004 (Leconotide) causes antihyperalgesia without side effects when given intravenously: a comparison with ziconotide in a rat model of diabetic neuropathic pain.	2010 Feb	20002322
Intravenous injection of leconotide, an omega conotoxin: synergistic antihyperalgesic effects with morphine in a rat model of bone cancer pain.	2011 Jun	21539704

Substance Class	Protein Created by `admin` on `Sat Dec 16 01:43:20 GMT 2023` Edited by `admin` on `Sat Dec 16 01:43:20 GMT 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	2P1P5JB93S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LECONOTIDE

Official Name

English

leconotide [INN]

Common Name

English

OMEGA-CONOPEPTIDE MVIIA

Common Name

English

Code System Code Type Description

INN

8095