U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 13:27:12 GMT 2023
Edited
by admin
on Sat Dec 16 13:27:12 GMT 2023
Nucleic Acid Subtype
Sequence Type P0LYNUCLEOTIDE
Record UNII
2O4BE0K238
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VOLANESORSEN
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
ISIS 304801 FREE ACID
Code English
ISIS-304801
Code English
volanesorsen [INN]
Common Name English
ISIS 304801
Common Name English
VOLANESORSEN [MI]
Common Name English
Volanesorsen [WHO-DD]
Common Name English
VOLANESORSEN [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29703
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
NCI_THESAURUS C1291
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
FDA ORPHAN DRUG 480815
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
Code System Code Type Description
DRUG BANK
DB15067
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
FDA UNII
2O4BE0K238
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
DRUG CENTRAL
5335
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
ChEMBL
CHEMBL3544994
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
CAS
915430-78-3
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
MERCK INDEX
m12145
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
NCI_THESAURUS
C152904
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
PUBCHEM
121489236
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
USAN
BC-133
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
WIKIPEDIA
Volanesorsen
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
INN
10166
Created by admin on Sat Dec 16 13:27:12 GMT 2023 , Edited by admin on Sat Dec 16 13:27:12 GMT 2023
PRIMARY
Sugar Site Range Site Count
2'-O-Methoxyethyl ribose 1_1-1_5;1_16-1_20 10 / 20
Deoxyribose (DNA) 1_6-1_15 10 / 20
Linkage Site Range Site Count
Phosporothioate 1_2-1_20 19 / 19
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOSIDE SUBSTITUTION [1_3] C 2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE AOQ54IZZ6J
NUCLEOSIDE SUBSTITUTION [1_6] [1_11] [1_12] [1_15] C 5-METHYLDEOXYCYTIDINE B200GV71QM