VOLANESORSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Tue Apr 01 20:41:04 GMT 2025` Edited by `admin` on `Tue Apr 01 20:41:04 GMT 2025`
Sequence Type	P0LYNUCLEOTIDE
Record UNII	2O4BE0K238
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ISIS 304801 FREE ACID

Preferred Name

English

VOLANESORSEN

Official Name

English

ISIS-304801

Code

English

volanesorsen [INN]

Common Name

English

ISIS 304801

Common Name

English

VOLANESORSEN [MI]

Common Name

English

Volanesorsen [WHO-DD]

Common Name

English

VOLANESORSEN [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29703

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

NCI_THESAURUS

C1291

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

FDA ORPHAN DRUG

480815

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

Code System Code Type Description

DRUG BANK

DB15067

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

FDA UNII

2O4BE0K238

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

DRUG CENTRAL

5335

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

ChEMBL

CHEMBL3544994

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

CAS

915430-78-3

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

SMS_ID

100000173490

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

MERCK INDEX

m12145

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

NCI_THESAURUS

C152904

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

PUBCHEM

121489236

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

USAN

BC-133

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

WIKIPEDIA

Volanesorsen

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

INN

10166

Created by admin on Tue Apr 01 20:41:04 GMT 2025 , Edited by admin on Tue Apr 01 20:41:04 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_20	19 / 19

Related Record Type Details


					6JON30SLDT

VOLANESORSEN SODIUM

SALT/SOLVATE -> PARENT

Related Record Type Details


					2O4BE0K238

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE SUBSTITUTION	[1_3]		C		2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE	AOQ54IZZ6J
NUCLEOSIDE SUBSTITUTION	[1_6] [1_11] [1_12] [1_15]		C		5-METHYLDEOXYCYTIDINE	B200GV71QM