TETRAMETHYLUREA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H12N2O
Molecular Weight	116.1616
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)C(=O)N(C)C

InChI

InChIKey=AVQQQNCBBIEMEU-UHFFFAOYSA-N

InChI=1S/C5H12N2O/c1-6(2)5(8)7(3)4/h1-4H3

HIDE SMILES / InChI

Molecular Formula	C5H12N2O
Molecular Weight	116.1616
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Developmental toxicity study of tetramethylurea (TMU) in rats.	2001 Aug	11452398
Oligomerization of Escherichia coli enterotoxin b through its C-terminal hydrophobic alpha-helix.	2001 Feb 14	11342001
Spectrophotometric analysis of 5-coordinate cobalt(II) species for ligand substitution of hexakis(acetonitrile)cobalt(II) with bulky 1,1,3,3-tetramethylurea in noncoordinating nitromethane.	2001 Jan	11993661
Decomposition of alkyl-substituted urea molecules at a hydroxide-bridged dinickel center.	2001 Mar 12	11300826
Inhalation toxicity of tetramethylurea in rats.	2001 Nov	11665645
Characterization of the in vitro adhesion of Actinobacillus pleuropneumoniae to swine alveolar epithelial cells.	2002 Aug 2	12119138
Effect of urea, dimethylurea, and tetramethylurea on the phase behavior of dioleoylphosphatidylethanolamine.	2002 Feb	11934396
Lysozyme viscoelastic matrices in tetramethylurea/water media: a small angle X-ray scattering study.	2002 Oct 16	12377367
Rheological study on lysozyme/tetramethylurea viscoelastic matrices.	2002 Oct 16	12377364
Volatile metabolites of higher plant crops as a photosynthesizing life support system component under temperature stress at different light intensities.	2003	14503518
Ionic transacetalization with acylium ions: a class-selective and structurally diagnostic reaction for cyclic acetals performed under unique electrospray and atmospheric pressure chemical ionization in-source ion-molecule reaction conditions.	2003 Sep 1	14632085
Characterization of metal ions in coordinating solvent mixtures by means of Raman spectroscopy.	2004 Mar	15068281
Reactivity of a (mu-oxo)(mu-hydroxo)diiron(III) diamond core with water, urea, substituted ureas, and acetamide.	2004 Nov 1	15500359
The burden borne by urease.	2005 Aug 10	16076178
Ion/molecule reactions in a miniature RIT mass spectrometer.	2005 Nov	16255061
Structural modifications of aqueous ionic micelles in the presence of denaturants as studied by DLS and viscometry.	2005 Oct 11	16207020
The first total synthesis of the peptaibol hypomurocin A1 and its conformation analysis: an application of the 'azirine/oxazolone method'.	2005 Sep	17193196
Solvent-induced lysozyme gels: rheology, fractal analysis, and sol-gel kinetics.	2005 Sep 15	15935361
JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs.	2005 Sep 27	16188040
The atmospheric pressure Meerwein reaction.	2006 Apr	16498596
Solvent-induced lysozyme gels: effects of system composition and temperature on structural and dynamic characteristics.	2006 Dec 5	16802304
The adhesion of Pseudomonas aeruginosa to high molecular weight human tear film species corresponds to glycoproteins reactive with Sambucus nigra lectin.	2006 Nov	16844114
Performance evaluation of elemental analysis/isotope ratio mass spectrometry methods for the determination of the D/H ratio in tetramethylurea and other compounds--results of a laboratory inter-comparison.	2007	17428013
First synthesis of tepidopterin [2'-O-(2-acetamido-2-deoxy-beta-d-glucopyranosyl)-L-threo-biopterin].	2007 Nov 5	17631283
Observation of immobilized water molecules around hydrophobic groups.	2007 Oct 5	17930728
Thermal signature of hydrophobic hydration dynamics.	2008 Aug 6	18624406
Strong slowing down of water reorientation in mixtures of water and tetramethylurea.	2008 Mar 20	18275169
Destabilization of the hydrogen-bond structure of water by the osmolyte trimethylamine N-oxide.	2009 Apr 2	19425246
Suppression of proton mobility by hydrophobic hydration.	2009 Dec 2	19929017
Investigating the hydrogen-bonding model of urea denaturation.	2009 Jul 8	19527028
Small-angle neutron scattering and volumetric studies of dilute solutions of N,N'-dimethylpropyleneurea in heavy water.	2009 Mar 12	19090683
[Solvent effects on raman spectroscopy of 1, 1,3, 3-tetramethylurea in organic solvents].	2009 May	19650475
Hydrophobic solvation: a 2D IR spectroscopic inquest.	2009 Sep 15	19681584
Bis(1,3-dimethyl-1,3-diazinan-2-one)dinitratodioxidouranium(VI).	2010 Dec 4	21522544
[Investigation of hydrophobic effect on the hydrogen-bond formation of 1,1,3,3-tetramethylurea by Raman methods].	2010 Jan	20302091
Effects of urea, tetramethyl urea, and trimethylamine N-oxide on aqueous solution structure and solvation of protein backbones: a molecular dynamics simulation study.	2010 Jan 14	19928871
The hydrogen bond network structure within the hydration shell around simple osmolytes: urea, tetramethylurea, and trimethylamine-N-oxide, investigated using both a fixed charge and a polarizable water model.	2010 Jul 21	20649360
Influence of concentration and temperature on the dynamics of water in the hydrophobic hydration shell of tetramethylurea.	2010 Nov 10	20949942

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:22:53 GMT 2023` Edited by `admin` on `Fri Dec 15 18:22:53 GMT 2023`
Record UNII	2O1EJ64031
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TETRAMETHYLUREA

Systematic Name

English

TETRAMETHYLCARBAMIDE

Common Name

English

TETRAMETHYLUREA [HSDB]

Common Name

English

N,N,N',N'-TETRAMETHYLUREA

Systematic Name

English

TEMUR

Common Name

English

NSC-91488

Code

English

TETRAMETHYLUREA [MI]

Common Name

English

TMU

Common Name

English

TETRAMETHYLUREA, 1,1,3,3-

Systematic Name

English

Code System Code Type Description

PUBCHEM

12437