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Details

Stereochemistry ACHIRAL
Molecular Formula C7H10N2.2ClH
Molecular Weight 195.09
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,6-TOLUENEDIAMINE DIHYDROCHLORIDE

SMILES

Cl.Cl.CC1=C(N)C=CC=C1N

InChI

InChIKey=LXIJUYQULXUMDO-UHFFFAOYSA-N
InChI=1S/C7H10N2.2ClH/c1-5-6(8)3-2-4-7(5)9;;/h2-4H,8-9H2,1H3;2*1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C7H10N2
Molecular Weight 122.1677
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.
2010-09-30
Determination of aromatic amines in aqueous extracts of polyurethane foam using hydrophilic interaction liquid chromatography and mass spectrometry.
2010-09-23
Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers.
2010-03
Syrian hamster embryo (SHE) cell transformation assay with conditioned media (without X-ray irradiated feeder layer) using 2,4-diaminotoluene, 2,6-diaminotoluene and chloral hydrate.
2008-07-31
Biological monitoring of TDI-derived amines in polyurethane foam production.
2007-09
Removal of dinitrotoluenes from water via reduction with iron and peroxidase-catalyzed oxidative polymerization: a comparison between Arthromyces ramosus peroxidase and soybean peroxidase.
2007-04
Differences in gene expression profiles in the liver between carcinogenic and non-carcinogenic isomers of compounds given to rats in a 28-day repeat-dose toxicity study.
2006-12-15
Induction of LacZ mutations in Muta Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes.
2006-09-19
Ab initio MO analysis of the excited electronic states of high-spin quintet 2-methylphenylene-1,3-dinitrene.
2006-03-27
Risk evaluation of occupational exposure to methylene dianiline and toluene diamine in polyurethane foam.
2005-12
Upper reference limits for biomarkers of exposure to aromatic diisocyanates.
2005-08
Improvement in the GC-MS method for determining urinary toluene-diamine and its application to the biological monitoring of workers exposed to toluene-diisocyanate.
2005-07
Biological monitoring of exposure to toluene diisocyanate.
2004-10
Hydrolytic stability of toluene diisocyanate and polymeric methylenediphenyl diisocyanate based polyureas under environmental conditions.
2004-02-15
[Assessment of the emission of volatile organic compounds from polyurethane foams].
2004
Development, validation and characterization of an analytical method for the quantification of hydrolysable urinary metabolites and plasma protein adducts of 2,4- and 2,6-toluene diisocyanate, 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate.
2003-08-29
Biological monitoring of aromatic diisocyanates in workers exposed to thermal degradation products of polyurethanes.
2002-10
LC-MS determination of urinary toluenediamine in workers exposed to toluenediisocyanate.
2002-08-05
Organic analysis by ion chromatography. 1. Determination of aromatic amines and aromatic diisocyanates by cation-exchange chromatography with amperometric detection.
2002-05-17
Exposure to 2,4- and 2,6-toluene diisocyanate (TDI) during production of flexible foam: determination of airborne TDI and urinary 2,4- and 2,6-toluenediamine (TDA).
2001-07
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:46:33 GMT 2025
Edited
by admin
on Mon Mar 31 21:46:33 GMT 2025
Record UNII
2NR4TK287E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2,6-DIAMINOTOLUENE DIHYDROCHLORIDE [HSDB]
Preferred Name English
2,6-TOLUENEDIAMINE DIHYDROCHLORIDE
Systematic Name English
1,3-BENZENEDIAMINE, 2-METHYL-, DIHYDROCHLORIDE
Systematic Name English
TOLUENE-2,6-DIAMINE, DIHYDROCHLORIDE
Systematic Name English
2-METHYLBENZENE-1,3-DIAMINE DIHYDROCHLORIDE
Systematic Name English
1,3-BENZENEDIAMINE, 2-METHYL-, HYDROCHLORIDE (1:2)
Systematic Name English
Code System Code Type Description
FDA UNII
2NR4TK287E
Created by admin on Mon Mar 31 21:46:33 GMT 2025 , Edited by admin on Mon Mar 31 21:46:33 GMT 2025
PRIMARY
PUBCHEM
27324
Created by admin on Mon Mar 31 21:46:33 GMT 2025 , Edited by admin on Mon Mar 31 21:46:33 GMT 2025
PRIMARY
EPA CompTox
DTXSID4020404
Created by admin on Mon Mar 31 21:46:33 GMT 2025 , Edited by admin on Mon Mar 31 21:46:33 GMT 2025
PRIMARY
CAS
15481-70-6
Created by admin on Mon Mar 31 21:46:33 GMT 2025 , Edited by admin on Mon Mar 31 21:46:33 GMT 2025
PRIMARY
HSDB
6194
Created by admin on Mon Mar 31 21:46:33 GMT 2025 , Edited by admin on Mon Mar 31 21:46:33 GMT 2025
PRIMARY
ECHA (EC/EINECS)
239-505-8
Created by admin on Mon Mar 31 21:46:33 GMT 2025 , Edited by admin on Mon Mar 31 21:46:33 GMT 2025
PRIMARY