Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H3Cl5O2 |
| Molecular Weight | 356.416 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC2=C(OC3=C(Cl)C(Cl)=C(Cl)C=C3O2)C=C1Cl
InChI
InChIKey=FSPZPQQWDODWAU-UHFFFAOYSA-N
InChI=1S/C12H3Cl5O2/c13-4-1-7-8(2-5(4)14)19-12-9(18-7)3-6(15)10(16)11(12)17/h1-3H
| Molecular Formula | C12H3Cl5O2 |
| Molecular Weight | 356.416 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Consensus toxicity factors for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls combining in silico models and extensive in vitro screening of AhR-mediated effects in human and rodent cells. | 2015-04-20 |
|
| Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells. | 2014-04-07 |
|
| Comparison of intake and systemic relative effect potencies of dioxin-like compounds in female mice after a single oral dose. | 2013-07 |
|
| Apportionment of TEQs from four major dioxin sources in Japan on the basis of five indicative congeners. | 2010-11 |
|
| [The levels of dioxin in 60 human breast milk samples and the exposure risk factor analysis in Shenzhen]. | 2010-03 |
|
| Factorial design applied for multiple endpoint toxicity evaluation in Atlantic salmon (Salmo salar L.) hepatocytes. | 2009-12 |
|
| The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy. | 2009-09 |
|
| Determination of some congeners of polychlorinated dibenzo-p-dioxins (PCDDs) in milk using gas chromatography. | 2009-06 |
|
| Comparison of immunotoxicity among tetrachloro-, pentachloro-, tetrabromo- and pentabromo-dibenzo-p-dioxins in mice. | 2009-02-04 |
|
| Relative potency based on hepatic enzyme induction predicts immunosuppressive effects of a mixture of PCDDS/PCDFS and PCBS. | 2008-03-15 |
|
| The acute lethality and endocrine effect of 1,2,3,7,8-PeCDD in juvenile goldfish (Carassius auratus) in vivo. | 2008 |
|
| Dietary uptake of dioxins (PCDD/PCDFs) and dioxin-like PCBs in Spanish aquacultured turbot (Psetta maxima). | 2007-04 |
|
| Assigning concentration values for dioxin and furan congeners in human serum when measurements are below limits of detection: an observational approach. | 2007-03 |
|
| Body mass index and serum chlorinated dibenzo-p-dioxin and dibenzofuran levels. | 2007-01 |
|
| In utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin induces amphiregulin gene expression in the developing mouse ureter. | 2006-11 |
|
| Cell-free bioassay for measurement of dioxins based on fluorescence enhancement of fluorescein isothiocyanate-labeled DNA probe. | 2006-10-15 |
|
| Estimated cancer risk of dioxins to humans using a bioassay and physiologically based pharmacokinetic model. | 2006-07-15 |
|
| PCB, PCDD and PCDF residues in fin and non-fin fish products from the Canadian retail market 2002. | 2006-04-15 |
|
| Breast milk dioxins in Hong Kong and Pearl River Delta. | 2006-02 |
|
| Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels. | 2005-07 |
|
| Enzyme-linked immunosorbent assay for monitoring toxic dioxin congeners in milk based on a newly generated monoclonal anti-dioxin antibody. | 2004-04-01 |
|
| Evaluation of toxic equivalency factors for induction of cytochromes P450 CYP1A1 and CYP1A2 enzyme activity by dioxin-like compounds. | 2004-01-15 |
|
| Comparison of accumulation and altered steroid secretion by placental tissue treated with TCDD and natural mixture of PCDDs-PCDFs. | 2003-11 |
|
| A mixture of dioxins, furans, and non-ortho PCBs based upon consensus toxic equivalency factors produces dioxin-like reproductive effects. | 2003-07 |
|
| Harnessing microbial appetites for remediation. | 2003-03 |
|
| Reductive dehalogenation of chlorinated dioxins by an anaerobic bacterium. | 2003-01-23 |
|
| Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains. | 2002-05-15 |
|
| Dioxin exposure in a residential community. | 2001-06-19 |
|
| Disposition of polychlorinated dibenzo-p-dioxins, dibenzofurans, and non-ortho polychlorinated biphenyls in pregnant long evans rats and the transfer to offspring. | 2001-06-01 |
|
| Relative potencies of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners to induce cytochrome P4501A mRNA in a zebrafish liver cell line. | 2001-05 |
|
| Correlation of cardiotoxicity mediated by halogenated aromatic hydrocarbons to aryl hydrocarbon receptor activation. | 2001-05 |
|
| Induction of 7-ethoxyresorufin-O-deethylase activity by planar chlorinated hydrocarbons and polycyclic aromatic hydrocarbons in cell lines from the rainbow trout pituitary. | 2001-02 |
|
| Alterations in the growth factor signal transduction pathways and modulators of the cell cycle in endocervical cells from macaques exposed to TCDD. | 1998-08 |
|
| Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway. | 1996-11-22 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:53:00 GMT 2025
by
admin
on
Mon Mar 31 18:53:00 GMT 2025
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| Record UNII |
2NE6H0QPCH
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| Record Status |
Validated (UNII)
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| Record Version |
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C051452
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DTXSID7052078
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