U.S. Department of Health & Human Services
National Institutes of Health
NCATS
This repository is under review for potential modification in compliance with Administration directives.
Dismiss
Return Home
Inxight
Drugs
Search Substances
Home
Browse Drugs
US Approved Drugs
Marketed Drugs
Investigational Drugs
All Substances
Search
Structure Search
Sequence Search
Downloads
About
Search Substances
MATRIX METALLOPEPTIDASE 12
2ND7C9F8S9
Other
General
Record Details
Names
5
Identifiers
1
Subunits
1
Glycosylation
1
Relationships
6
Modifications
2
Characteristic Attributes
2
MATRIX METALLOPEPTIDASE 12
2ND7C9F8S9
Other
General
Approval Year
Unknown
149,124
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
2ND7C9F8S9
Record Status
Validated (UNII)
Record Version
12
11
10
9
8
7
6
5
4
3
2
1
Names
5
Show
5
20
100
All
entries
Name
Type
Language
Name
Type
Language
MATRIX METALLOPEPTIDASE 12
Common Name
English
MACROPHAGE METALLOELASTASE
Preferred Name
English
MMP12
Common Name
English
MMP-12
Common Name
English
MATRIX METALLOPEPTIDASE 12 (HOMO SAPIENS (HUMAN))
Common Name
English
Showing 1 to 5 of 5 entries
Previous
1
Next
Identifiers
1
Show
5
20
100
All
entries
Code System
Code
Type
Description
Code System
Code
Type
Description
FDA UNII
2ND7C9F8S9
PRIMARY
Showing 1 to 1 of 1 entries
Previous
1
Next
Subunits
1
Subunit 0
>SUBUNIT_0
Glycosylation
1
Glycosylation Type
HUMAN
Show
5
20
100
All
entries
Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_179
Showing 1 to 1 of 1 entries
Previous
1
Next
Relationships
6
Show
5
20
100
All
entries
Related Record
Type
Details
Related Record
Type
Details
W2WJ6ME4K7
UK-370106
INHIBITOR -> TARGET
Qualification:
IC50
Amount:
42 NANOMOLAR (average)
B4OQY51WZS
AZD-1236
INHIBITOR -> TARGET
Amount:
SHARK CARTILAGE EXTRACT
INHIBITOR -> TARGET
Amount:
2IZ5925NZQ
Aderamastat
INHIBITOR -> TARGET
Amount:
EI4HZ6P03E
ALDUMASTAT
INHIBITOR -> TARGET
Amount:
Showing 1 to 5 of 6 entries
Previous
1
2
Next
Modifications
2
Structural Modifications
Show
5
20
100
All
entries
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
MOIETY
Amount:
MOLE PER SUBUNIT 4 MOLES PER SUBUNIT (average)
CALCIUM CATION
2M83C4R6ZB
MOIETY
Amount:
MOLE PER SUBUNIT 2 MOLES PER SUBUNIT (average)
ZINC CATION
13S1S8SF37
Showing 1 to 2 of 2 entries
Previous
1
Next
Characteristic Attributes
2
Show
5
20
100
All
entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)
CHEMICAL
NUMBER AVERAGE 42500 DA (average)
Molecular Formula
CHEMICAL
ESTIMATED
C1944H2861O534N507S7
Showing 1 to 2 of 2 entries
Previous
1
Next
