DEMOXYTOCIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C43H65N11O12S2
Molecular Weight	992.173
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]1(NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)[C@@H](C)CC

InChI

InChIKey=GTYWGUNQAMYZPF-QPLNMOKZSA-N

InChI=1S/C43H65N11O12S2/c1-5-23(4)36-42(65)49-26(12-13-32(44)56)38(61)50-29(19-33(45)57)39(62)52-30(21-68-67-16-14-35(59)48-28(40(63)53-36)18-24-8-10-25(55)11-9-24)43(66)54-15-6-7-31(54)41(64)51-27(17-22(2)3)37(60)47-20-34(46)58/h8-11,22-23,26-31,36,55H,5-7,12-21H2,1-4H3,(H2,44,56)(H2,45,57)(H2,46,58)(H,47,60)(H,48,59)(H,49,65)(H,50,61)(H,51,64)(H,52,62)(H,53,63)/t23-,26-,27-,28-,29-,30-,31-,36-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C43H65N11O12S2
Molecular Weight	992.173
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 8
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/42577 | https://www.ncbi.nlm.nih.gov/pubmed/468056 | https://www.sciencedirect.com/science/article/pii/000293786790107X

Demoxytocin is a synthetic analog of a peptide hormone oxytocin. The drug possesses higher oxytocin and lower vasopressin activity than oxytocin and is not broken down by leucylaminopeptidase or serum oxytocinase. Demoxytocin is administered as a buccal tablet formulation and is used for the induction of labor in overdue pregnancies, to prevent and treat puerperal mastitis and to promote lactation.

Approval Year

PubMed

Title	Date	PubMed
REVIEW: Oxytocin: Crossing the bridge between basic science and pharmacotherapy.	2010 Oct	20626426

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:12:31 GMT 2023` Edited by `admin` on `Fri Dec 15 15:12:31 GMT 2023`
Record UNII	2N9HM3X95F
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DEMOXYTOCIN

Official Name

English

SANDOPART

Brand Name

English

1-(3-MERCAPTOPROPIONIC ACID)OXYTOCIN

Common Name

English

OXYTOCIN, 1-(3-MERCAPTOPROPIONIC ACID)-

Common Name

English

demoxytocin [INN]

Common Name

English

DESAMINOOXYTOCIN

Common Name

English

1-DEAMINOOXYTOCIN

Common Name

English

OXYTOCIN, 1-(3-MERCAPTOPROPANOIC ACID)-

Common Name

English

1-(3-MERCAPTOPROPIONIC ACID)-OXYTOCIN

Common Name

English

DEMOXYTOCIN [MART.]

Common Name

English

Demoxytocin [WHO-DD]

Common Name

English

OXYTOCIN, DEAMINO-

Common Name

English

DEAMINOOXYTOCIN [MI]

Common Name

English

ODA 914

Code

English

ODA-914

Code

English

Classification Tree Code System Code

WHO-ATC

H01BB01