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Details

Stereochemistry UNKNOWN
Molecular Formula C19H21NO6
Molecular Weight 359.3731
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OXODIPINE, (+)-

SMILES

CCOC(=O)C1=C(C)NC(C)=C(C1C2=C3OCOC3=CC=C2)C(=O)OC

InChI

InChIKey=MSOAVHHAZCMHDI-UHFFFAOYSA-N
InChI=1S/C19H21NO6/c1-5-24-19(22)15-11(3)20-10(2)14(18(21)23-4)16(15)12-7-6-8-13-17(12)26-9-25-13/h6-8,16,20H,5,9H2,1-4H3

HIDE SMILES / InChI

Molecular Formula C19H21NO6
Molecular Weight 359.3731
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Oxodipine is a dihydropyridine calcium channel blocker that has been developed by IQB as an antihypertensive agent. Experiments on dogs have shown that oxodipine exerted a relatively specific action on blood vessels without significant intrinsic negative chronotropic properties. in addition, in Europe, the drug was involved in phase III clinical trials in and in phase II for the treatment of Hypertension. Besides, oxodipine was studied for the treatment of ischaemic heart disorders. However, these studied were discontinued.

Approval Year

PubMed

PubMed

TitleDatePubMed
Effect of oxodipine, a novel dihydropyridine calcium channel blocker, in neurogenic hypertensive dogs.
1993 Jan-Feb
Characteristics of Ca2+ channel blockade by oxodipine and elgodipine in rat cardiomyocytes.
1998 Sep 11
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 10:24:59 GMT 2023
Edited
by admin
on Sat Dec 16 10:24:59 GMT 2023
Record UNII
2MTW8YSX8G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OXODIPINE, (+)-
Common Name English
3,5-PYRIDINEDICARBOXYLIC ACID, 4-(1,3-BENZODIOXOL-4-YL)-1,4-DIHYDRO-2,6-DIMETHYL-, ETHYL METHYL ESTER, (+)-
Systematic Name English
Code System Code Type Description
PUBCHEM
56108
Created by admin on Sat Dec 16 10:24:59 GMT 2023 , Edited by admin on Sat Dec 16 10:24:59 GMT 2023
PRIMARY
FDA UNII
2MTW8YSX8G
Created by admin on Sat Dec 16 10:24:59 GMT 2023 , Edited by admin on Sat Dec 16 10:24:59 GMT 2023
PRIMARY
CAS
119914-33-9
Created by admin on Sat Dec 16 10:24:59 GMT 2023 , Edited by admin on Sat Dec 16 10:24:59 GMT 2023
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER
ENANTIOMER -> ENANTIOMER