RENIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 16:31:46 GMT 2025` Edited by `admin` on `Tue Apr 01 16:31:46 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	2MS130CE0A
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

RENIN

Common Name

English

ANGIOTENSINOGENASE

Preferred Name

English

RENIN [MI]

Common Name

English

HUMAN RENIN

Common Name

English

Classification Tree Code System Code

LOINC

35570-1

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

LOINC

30895-7

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

LOINC

2915-7

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

LOINC

12249-9

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

LOINC

30894-0

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

Code System Code Type Description

PHAROS

P00797

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

PRIMARY

UNIPROT

P00797

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

PRIMARY

DAILYMED

2MS130CE0A

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

PRIMARY

MERCK INDEX

m9523

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

PRIMARY

FDA UNII

2MS130CE0A

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

PRIMARY

SMS_ID

100000183347

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

PRIMARY

CAS

9015-94-5

Created by admin on Tue Apr 01 16:31:46 GMT 2025 , Edited by admin on Tue Apr 01 16:31:46 GMT 2025

PRIMARY

From	To
1_51	1_58
1_217	1_221
1_259	1_296

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_5
N	1_75

Related Record Type Details


					49R6GO0FWP

CP-108671 FREE BASE

INHIBITOR -> TARGET


					01IC75R817

INHIBITOR -> TARGET


					LC7FBL96A4

REMIKIREN

INHIBITOR -> TARGET

Amount:


					502FWN4Q32

ALISKIREN

INHIBITOR -> TARGET


					C2M78A9V6Z

Sitokiren

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					I36B16A34Q

ZANKIREN

INHIBITOR -> TARGET

Comments:

A-72517 is a potent inhibitor of human renin (IC50 = 1.0 nmol/L, pH 7.4 in plasma)

Qualification:

IC50

Amount:


					K259Z4O1B3

INHIBITOR -> TARGET

Comments:

Ciprokinen inhibited human renin in a buffer and human plasma with an IC50 of 0.07 and 0.65 nmol/L, respectively.

Qualification:

IC50

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL