MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 22:56:04 GMT 2025` Edited by `admin` on `Tue Apr 01 22:56:04 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type	IMMUNOMODULATOR
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	2LEG6M8GXU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1

Common Name

English

MALT LYMPHOMA-ASSOCIATED TRANSLOCATION

Preferred Name

English

MALT1

Common Name

English

PARACASPASE

Common Name

English

MALT1 PROTEASE

Common Name

English

Code System Code Type Description

FDA UNII

2LEG6M8GXU

Created by admin on Tue Apr 01 22:56:04 GMT 2025 , Edited by admin on Tue Apr 01 22:56:04 GMT 2025

PRIMARY

From	To
1_146	1_189
1_247	1_289

Related Record Type Details


					9A59ESA73N

SGR-1505

INHIBITOR -> TARGET

Interaction Type:

ALLOSTERIC

Amount:


					L9790S42AI

SAFIMALTIB

INHIBITOR -> TARGET

Comments:

Inhibits proliferation of activated B-cell diffuse large B-cell lymphoma (ABC-DLBCL) cell lines bearing CD79b or CARD11 mutations. Dose dependent inhibition of the generation of Tregs (CD4+CD25+FoxP3+) following CD3/28 stimulation.

Interaction Type:

ALLOSTERIC

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS			N-ACETYLSERINE	W98518XGZ3

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL