U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
YTTRIUM Y-90 (YTRACIS®, YTTRIGA®) is a radioactive form of the chemical element yttrium. It is used for radiolabelling other medicines. An example of its use is the treatment of some type of tumors, where the radiolabelled medicine carries the radioactivity to the site of a tumor to destroy the tumor cells.

Approval Year

Substance Class Protein
Created
by admin
on Fri Dec 15 19:16:20 GMT 2023
Edited
by admin
on Fri Dec 15 19:16:20 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
2L271110ED
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
YTTRIUM Y-90 CLIVATUZUMAB TETRAXETAN
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN MUCIN MUC1) (HUMAN-MOUSE MONOCLONAL HPAM4 HEAVY CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL HPAM4 .KAPPA.-CHAIN, DIMER, 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID CONJUGATE, YTTRIUM-SUP(90)Y CHELATE
Common Name English
yttrium (⁹⁰Y) clivatuzumab tetraxetan [INN]
Common Name English
Y-90 HPAM4
Common Name English
S9S0HY-PAM4
Code English
HPAM-4-DOTA
Code English
90Y-HPAM4
Code English
90HY-PAM4
Code English
YTTRIUM (90Y) CLIVATUZUMAB TETRAXETAN
INN  
INN  
Official Name English
YTTRIUM Y 90 CLIVATUZUMAB TETRAXETAN
USAN  
USAN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN MUCIN MUC1) (HUMAN-MOUSE MONOCLONAL HPAM4 HEAVY CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL HPAM4 .KAPPA.-CHAIN, DIMER, 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID CONJUGATE, YTTRIUM-SUP(90)Y CHELATE
Common Name English
IMMU-107
Code English
CONJ:MAB HUMANIZED (IGG1) ANTI P15941 (MUC1_HUMAN); YTTRIUM Y 90 (IMMU107)
Common Name English
YTTRIUM Y 90 CLIVATUZUMAB TETRAXETAN [USAN]
Common Name English
PAN-CIDE
Brand Name English
90Y-HPAMA4
Code English
HPAM4-DOTA
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 178503
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
NCI_THESAURUS C1511
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
NCI_THESAURUS C129819
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
Code System Code Type Description
FDA UNII
2L271110ED
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
PRIMARY
CAS
943976-23-6
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
PRIMARY
INN
9226
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
PRIMARY
DRUG BANK
DB15368
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
PRIMARY
USAN
WW-15
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
PRIMARY
NCI_THESAURUS
C48429
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
PRIMARY
ChEMBL
CHEMBL2108708
Created by admin on Fri Dec 15 19:16:20 GMT 2023 , Edited by admin on Fri Dec 15 19:16:20 GMT 2023
PRIMARY
From To
1_22 1_96
1_146 1_202
1_222 3_215
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
2_22 2_96
2_146 2_202
2_222 4_215
2_263 2_323
2_369 2_427
3_23 3_89
3_135 3_195
4_23 4_89
4_135 4_195
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
TARGET->RADIOLIGAND
DERIVATIVE -> PARENT
TARGET->LIGAND
DERIVATIVE -> PARENT
Related Record Type Details
ACTIVE MOIETY
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL