NICOTINAMIDE MONONUCLEOTIDE

Possibly Marketed Outside US

First approved in 2019

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H15N2O8P
Molecular Weight	334.2192
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NICOTINAMIDE MONONUCLEOTIDE

Structure Search

SMILES

NC(=O)C1=C[N+](=CC=C1)[C@@H]2O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]2O

InChI

InChIKey=DAYLJWODMCOQEW-TURQNECASA-N

InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C11H15N2O8P
Molecular Weight	334.2192
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.	2013-12	23834033
Resistin impairs SIRT1 function and induces senescence-associated phenotype in hepatocytes.	2013-09-05	23827175
A urinary metabonomics study on biochemical changes in yeast-induced pyrexia rats: a new approach to elucidating the biochemical basis of the febrile response.	2013-06-25	23583517
Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo.	2009-05-15	19426698
Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866.	2006-09-08	16901503
Postmortem production of ethanol and n-propanol in the brain of drowned persons.	2004-06	15166764
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans.	2004-05-14	15137942
Chemical diagnosis of Lesch-Nyhan syndrome using gas chromatography-mass spectrometry detection.	2003-07-15	12829005
Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN.	2002-04-10	11959140
The antitumor drug, 1,3-bis(2-chloroethyl)-1-nitroso-urea, inactivates human nicotinamide mononucleotide adenylyltransferase.	1995-02-14	7872964
Volatile compounds detected in blood of drunk drivers by headspace/capillary gas chromatography/ion trap mass spectrometry.	1991-11	1799580

Substance Class	Chemical Created by `admin` on `Wed Apr 02 17:55:58 GMT 2025` Edited by `admin` on `Wed Apr 02 17:55:58 GMT 2025`
Record UNII	2KG6QX4W0V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NICOTINAMIDE MONONUCLEOTIDE

Official Name

English

NMN [MI]

Preferred Name

English

3-(AMINOCARBONYL)-1-(5-O-PHOSPHONO-.BETA.-D-RIBOFURANOSYL)PYRIDINIUM INNER SALT

Systematic Name

English

.BETA.-D-NMN

Common Name

English

NICOTINAMIDE RIBONUCLEOSIDE 5'-PHOSPHATE

Common Name

English

NICOTINAMIDE RIBOTIDE

Common Name

English

.BETA.-NMN

Common Name

English

PYRIDINIUM, 3-(AMINOCARBONYL)-1-(5-O-PHOSPHONO-.BETA.-D-RIBOFURANOSYL)-, INNER SALT

Systematic Name

English

NMN

Common Name

English

Code System Code Type Description

DAILYMED

2KG6QX4W0V