INDOPANOLOL

CC1=C(Cl)C2=C(N1)C=CC=C2OCC(O)CNCCOC3=CC=CC=C3

InChIKey=KTODVGFADXOWDU-UHFFFAOYSA-N

InChI=1S/C20H23ClN2O3/c1-14-20(21)19-17(23-14)8-5-9-18(19)26-13-15(24)12-22-10-11-25-16-6-3-2-4-7-16/h2-9,15,22-24H,10-13H2,1H3

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Indopanolol is indole derivative patented by German pharmaceutical company Sandoz-Patent-G.m.b.H. as α- and β-adrenergic receptor blocking agent.

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor beta 87 Target ID: CHEMBL2094118 Sources: https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2044926&blobtype=pdf \| https://link.springer.com/content/pdf/10.1007%2FBF01146176.pdf \| https://link.springer.com/book/10.1007/978-1-4757-2085-3	Antagonist 2778
Adrenergic receptor alpha 64 Target ID: CHEMBL2095203 Sources: https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2044926&blobtype=pdf \| https://link.springer.com/content/pdf/10.1007%2FBF01146176.pdf \| https://link.springer.com/book/10.1007/978-1-4757-2085-3	Antagonist 2778

PubMed

Title	Date	PubMed
Atom, atom-type, and total nonstochastic and stochastic quadratic fingerprints: a promising approach for modeling of antibacterial activity.	2005 Apr 15	15781398

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:09:54 UTC 2023` Edited by `admin` on `Fri Dec 15 16:09:54 UTC 2023`
Record UNII	2JQ3661CAD
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

INDOPANOLOL

Official Name

English

indopanolol [INN]

Common Name

English

(±)-1-((3-CHLORO-2-METHYLINDOL-4-YL)OXY)-3-((2-PHENOXYETHYL)AMINO)-2-PROPANOL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29576