PROCLONOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H14Cl2O
Molecular Weight	293.188
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(C1CC1)(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3

InChI

InChIKey=BKAYSPSVVJBHHK-UHFFFAOYSA-N

InChI=1S/C16H14Cl2O/c17-14-7-3-12(4-8-14)16(19,11-1-2-11)13-5-9-15(18)10-6-13/h3-11,19H,1-2H2

HIDE SMILES / InChI

Molecular Formula	C16H14Cl2O
Molecular Weight	293.188
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3892282 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19661122&CC=US&NR=3287213A&KC=A | https://www.ncbi.nlm.nih.gov/pubmed/16596349

Proclonol is a cyclopropylmethanol derivative patented by Belgium pharmaceutical company Janssen Pharmaceutica N. V. as an arachnicide and fungicide. Tetranychus urticae in the adult stage on bean plants were killed within 3 days with a spray contg. 35 ppm. Proclonol, while all of the larval stage on strawberry leaves was killed by 62.5 ppm., and no eggs sprayed with 40 ppm. hatched. A suspension of 500 ppm. Proclonol used to dip strawberry leaves infested with Tarsonemus pallidus killed 96.2% of the mites.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Tetranychus cinnabarinus 1 Target ID: CHEMBL2367173 Sources: https://link.springer.com/article/10.1007/BF02981125	Inhibitor 8504

PubMed

Title	Date	PubMed
On the genotoxicity of the pesticides Endodan and Kilacar in 6 different test systems.	1985-07	3892282

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:44:11 GMT 2025` Edited by `admin` on `Mon Mar 31 18:44:11 GMT 2025`
Record UNII	2IGW7XIE2Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4,4'-DICHLORO-.ALPHA.-CYCLOPROPYLBENZHYDROL

Preferred Name

English

PROCLONOL

Official Name

English

R-8284

Code

English

4-CHLORO-.ALPHA.-(4-CHLOROPHENYL)-.ALPHA.-CYCLOPROPYLBENZENEMETHANOL

Systematic Name

English

BENZENEMETHANOL, 4-CHLORO-.ALPHA.-(4-CHLOROPHENYL)-.ALPHA.-CYCLOPROPYL-

Systematic Name

English

BIS(P-CHLOROPHENYL)CYCLOPROPYLMETHANOL

Common Name

English

PROCLONOL [USAN]

Common Name

English

proclonol [INN]

Common Name

English

R 8284

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C737