U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C16H14Cl2O
Molecular Weight 293.188
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROCLONOL

SMILES

OC(C1CC1)(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3

InChI

InChIKey=BKAYSPSVVJBHHK-UHFFFAOYSA-N
InChI=1S/C16H14Cl2O/c17-14-7-3-12(4-8-14)16(19,11-1-2-11)13-5-9-15(18)10-6-13/h3-11,19H,1-2H2

HIDE SMILES / InChI

Molecular Formula C16H14Cl2O
Molecular Weight 293.188
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Proclonol is a cyclopropylmethanol derivative patented by Belgium pharmaceutical company Janssen Pharmaceutica N. V. as an arachnicide and fungicide. Tetranychus urticae in the adult stage on bean plants were killed within 3 days with a spray contg. 35 ppm. Proclonol, while all of the larval stage on strawberry leaves was killed by 62.5 ppm., and no eggs sprayed with 40 ppm. hatched. A suspension of 500 ppm. Proclonol used to dip strawberry leaves infested with Tarsonemus pallidus killed 96.2% of the mites.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
On the genotoxicity of the pesticides Endodan and Kilacar in 6 different test systems.
1985 Jul
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:18:31 GMT 2023
Edited
by admin
on Fri Dec 15 17:18:31 GMT 2023
Record UNII
2IGW7XIE2Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROCLONOL
INN   USAN  
INN   USAN  
Official Name English
4,4'-DICHLORO-.ALPHA.-CYCLOPROPYLBENZHYDROL
Systematic Name English
R-8284
Code English
4-CHLORO-.ALPHA.-(4-CHLOROPHENYL)-.ALPHA.-CYCLOPROPYLBENZENEMETHANOL
Systematic Name English
BENZENEMETHANOL, 4-CHLORO-.ALPHA.-(4-CHLOROPHENYL)-.ALPHA.-CYCLOPROPYL-
Systematic Name English
BIS(P-CHLOROPHENYL)CYCLOPROPYLMETHANOL
Common Name English
PROCLONOL [USAN]
Common Name English
proclonol [INN]
Common Name English
R 8284
Code English
Classification Tree Code System Code
NCI_THESAURUS C737
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
Code System Code Type Description
CAS
14088-71-2
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
INN
2261
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
NCI_THESAURUS
C82303
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
PUBCHEM
26450
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
ECHA (EC/EINECS)
237-934-5
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
MESH
C045826
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
EVMPD
SUB10062MIG
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
EPA CompTox
DTXSID4057972
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
FDA UNII
2IGW7XIE2Y
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
ALANWOOD
proclonol
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
SMS_ID
100000081115
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105277
Created by admin on Fri Dec 15 17:18:31 GMT 2023 , Edited by admin on Fri Dec 15 17:18:31 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY