Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C8H14O2 |
| Molecular Weight | 142.1956 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCC(CC=C)C(O)=O
InChI
InChIKey=UMYDNZXEHYSVFY-UHFFFAOYSA-N
InChI=1S/C8H14O2/c1-3-5-7(6-4-2)8(9)10/h3,7H,1,4-6H2,2H3,(H,9,10)
| Molecular Formula | C8H14O2 |
| Molecular Weight | 142.1956 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| On the development of alternative antiepileptic drugs. Lack of enantioselectivity of the anticonvulsant activity, in contrast to teratogenicity, of 2-n-propyl-4-pentenoic acid and 2-n-propyl-4-pentynoic acid, analogues of the anticonvulsant drug valproic acid. | 1991 Jun |
|
| Differential effect of valproate and its Delta2- and Delta4-unsaturated metabolites, on the beta-oxidation rate of long-chain and medium-chain fatty acids. | 2001 Sep 28 |
|
| Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives. | 2005 May 15 |
|
| Science review: carnitine in the treatment of valproic acid-induced toxicity - what is the evidence? | 2005 Oct 5 |
|
| Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype. | 2006 Dec |
|
| The relationship between glucuronide conjugate levels and hepatotoxicity after oral administration of valproic acid. | 2009 Jul |
|
| Role of oxidative metabolism in the effect of valproic acid on markers of cell viability, necrosis, and oxidative stress in sandwich-cultured rat hepatocytes. | 2010 Dec |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:03:39 GMT 2023
by
admin
on
Sat Dec 16 08:03:39 GMT 2023
|
| Record UNII |
2GYI36I25W
|
| Record Status |
Validated (UNII)
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| Record Version |
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| Code System | Code | Type | Description | ||
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DTXSID20881257
Created by
admin on Sat Dec 16 08:03:39 GMT 2023 , Edited by admin on Sat Dec 16 08:03:39 GMT 2023
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1575-72-0
Created by
admin on Sat Dec 16 08:03:39 GMT 2023 , Edited by admin on Sat Dec 16 08:03:39 GMT 2023
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2GYI36I25W
Created by
admin on Sat Dec 16 08:03:39 GMT 2023 , Edited by admin on Sat Dec 16 08:03:39 GMT 2023
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PRIMARY | |||
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104896
Created by
admin on Sat Dec 16 08:03:39 GMT 2023 , Edited by admin on Sat Dec 16 08:03:39 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE TOXIC |
MINOR
URINE
|
