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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 15:29:25 GMT 2025
Edited
by admin
on Wed Apr 02 15:29:25 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin CANINE
Sequence Type COMPLETE
Record UNII
2GUH5YDW27
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZTS-00008183
Preferred Name English
Riltovetbart
INN  
Official Name English
immunoglobulin G2-kappa, anti-[Canis lupus familiaris IL31 (interleukin 31)], caninized monoclonal antibody
Common Name English
gamma2 heavy chain caninized (1-453) [VH (Canis lupus familiaris IGHV3-35*01 (89.6%) -(IGHD)-IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Canis lupus familiaris IGHG2*02, G2v2 CH3 H114 (CH1 (119-215), hinge 1-19 (216-234), CH2 (235-3
Common Name English
riltovetbart [INN]
Common Name English
Immunoglobulin G2 [440-histidine], anti-(Canis familiaris interleukin 31) (Canis familiaris-Mus musculus monoclonal ZTS-00008183 ?2-chain), disulfide with Canis familiaris-Mus musculus monoclonal ZTS-00008183 ?-chain, dimer
Common Name English
Code System Code Type Description
CAS
2641479-65-2
Created by admin on Wed Apr 02 15:29:25 GMT 2025 , Edited by admin on Wed Apr 02 15:29:25 GMT 2025
PRIMARY
NCI_THESAURUS
C190334
Created by admin on Wed Apr 02 15:29:25 GMT 2025 , Edited by admin on Wed Apr 02 15:29:25 GMT 2025
PRIMARY
SMS_ID
300000037999
Created by admin on Wed Apr 02 15:29:25 GMT 2025 , Edited by admin on Wed Apr 02 15:29:25 GMT 2025
PRIMARY
FDA UNII
2GUH5YDW27
Created by admin on Wed Apr 02 15:29:25 GMT 2025 , Edited by admin on Wed Apr 02 15:29:25 GMT 2025
PRIMARY
INN
12311
Created by admin on Wed Apr 02 15:29:25 GMT 2025 , Edited by admin on Wed Apr 02 15:29:25 GMT 2025
PRIMARY
From To
4_138 4_197
4_23 4_92
3_138 3_197
3_23 3_92
2_371 2_431
2_265 2_325
2_145 2_201
2_133 4_217
2_22 2_96
1_371 1_431
1_265 1_325
1_233 2_233
1_230 2_230
1_145 1_201
1_133 3_217
1_22 1_96
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
INTERLEUKIN 31 (CANINE)
TARGET -> INHIBITOR
Related Record Type Details
Riltovetbart
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID REMOVAL [1_453] [2_453] C-TERMINUS LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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