U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 11:28:23 GMT 2023
Edited
by admin
on Sat Dec 16 11:28:23 GMT 2023
Protein Type RECEPTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
2GI6VD3TEO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
C-X-C CHEMOKINE RECEPTOR TYPE 1
Common Name English
CXCR1
Common Name English
CXCR-1
Common Name English
HIGH AFFINITY INTERLEUKIN-8 RECEPTOR A
Common Name English
Code System Code Type Description
FDA UNII
2GI6VD3TEO
Created by admin on Sat Dec 16 11:28:23 GMT 2023 , Edited by admin on Sat Dec 16 11:28:23 GMT 2023
PRIMARY
UNIPROT
P25024
Created by admin on Sat Dec 16 11:28:23 GMT 2023 , Edited by admin on Sat Dec 16 11:28:23 GMT 2023
PRIMARY
From To
1_110 1_187
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_3
N 1_16
Related Record Type Details
INHIBITOR -> TARGET
NONCOMPETIVE BLOCKER OF THE ACTIVATION OF CXCR1 BY IL-8. DOES NOT BLOCK BINDING. PMN MIGRATION ASSAY.
ALLOSTERIC INHIBITOR
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL