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Details

Stereochemistry ACHIRAL
Molecular Formula C26H21F2N5O2S.ClH
Molecular Weight 542.0
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ODM-203 HYDROCHLORIDE

SMILES

Cl.CN1C=C(C=N1)C2=CC3=C(C=C2)N(C=N3)C4=CC(NS(=O)(=O)C5CC5)=CC(=C4)C6=CC=C(F)C=C6F

InChI

InChIKey=MGDFOHQZPLKQHE-UHFFFAOYSA-N
InChI=1S/C26H21F2N5O2S.ClH/c1-32-14-18(13-30-32)16-2-7-26-25(10-16)29-15-33(26)21-9-17(23-6-3-19(27)11-24(23)28)8-20(12-21)31-36(34,35)22-4-5-22;/h2-3,6-15,22,31H,4-5H2,1H3;1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C26H21F2N5O2S
Molecular Weight 505.539
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
149124
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
1539 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
200 mg single, oral
dose: 200 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE
food status: FED
2608 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
300 mg single, oral
dose: 300 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
1933 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
400 mg single, oral
dose: 400 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
3118 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
200 mg 1 times / day steady-state, oral
dose: 200 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE
food status: FED
4906 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
300 mg 1 times / day steady-state, oral
dose: 300 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
9070 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
400 mg 1 times / day steady-state, oral
dose: 400 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
25886 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
200 mg single, oral
dose: 200 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE
food status: FED
36708 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
300 mg single, oral
dose: 300 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
30257 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
400 mg single, oral
dose: 400 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
58612 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
200 mg 1 times / day steady-state, oral
dose: 200 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE
food status: FED
84233 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
300 mg 1 times / day steady-state, oral
dose: 300 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
170304 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/33262202/
400 mg 1 times / day steady-state, oral
dose: 400 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ODM-203 plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
Substance Class Chemical
Created
by admin
on Wed Apr 02 12:44:07 GMT 2025
Edited
by admin
on Wed Apr 02 12:44:07 GMT 2025
Record UNII
2G2VRT2ZFF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CYCLOPROPANESULFONAMIDE, N-(2',4'-DIFLUORO-5-(5-(1-METHYL-1H-PYRAZOL-4-YL)-1H-BENZIMIDAZOL-1-YL)(1,1'-BIPHENYL)-3-YL)-, HYDROCHLORIDE (1:1)
Preferred Name English
ODM-203 HYDROCHLORIDE
Common Name English
Code System Code Type Description
CAS
2412410-20-7
Created by admin on Wed Apr 02 12:44:07 GMT 2025 , Edited by admin on Wed Apr 02 12:44:07 GMT 2025
PRIMARY
FDA UNII
2G2VRT2ZFF
Created by admin on Wed Apr 02 12:44:07 GMT 2025 , Edited by admin on Wed Apr 02 12:44:07 GMT 2025
PRIMARY
PUBCHEM
156705211
Created by admin on Wed Apr 02 12:44:07 GMT 2025 , Edited by admin on Wed Apr 02 12:44:07 GMT 2025
PRIMARY
Related Record Type Details
Structure of ODM-203
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of ODM-203
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