Tametraline Hydrochloride

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C17H19N.ClH
Molecular Weight	273.8
Optical Activity	( + )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CN[C@@H]1CC[C@@H](C2=CC=CC=C2)C3=CC=CC=C13

InChI

InChIKey=XTSOELQVDLSJFM-SQQLFYIASA-N

InChI=1S/C17H19N.ClH/c1-18-17-12-11-14(13-7-3-2-4-8-13)15-9-5-6-10-16(15)17;/h2-10,14,17-18H,11-12H2,1H3;1H/t14-,17+;/m0./s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C17H19N
Molecular Weight	237.3395
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6492080 | https://www.genome.jp/dbget-bin/www_bget?drug+D02703

Tametraline (also known as CP-24,441) is a norepinephrine-dopamine reuptake inhibitor that was developed as an Antidepressant agent. Information about the current use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins.	1984-11	6492080
Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain.	1976-12	994022

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:22:11 GMT 2025` Edited by `admin` on `Mon Mar 31 19:22:11 GMT 2025`
Record UNII	2FY1A2A305
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Tametraline Hydrochloride

Official Name

English

CP-24,441-1

Preferred Name

English

1-Naphthalenamine, 1,2,3,4-tetrahydro-N-methyl-4-phenyl-, hydrochloride, (1R-trans)-

Systematic Name

English

(1R,4S)-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthylamine hydrochloride

Systematic Name

English

CP-24441-1

Code

English

TAMETRALINE HYDROCHLORIDE [MART.]

Common Name

English

TAMETRALINE HYDROCHLORIDE [USAN]

Common Name

English

1-Naphthalenamine, 1,2,3,4-tetrahydro-N-methyl-4-phenyl-, hydrochloride (1:1), (1R,4S)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265