HYDROXYLAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	H3NO
Molecular Weight	33.0299
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NO

InChI

InChIKey=AVXURJPOCDRRFD-UHFFFAOYSA-N

InChI=1S/H3NO/c1-2/h2H,1H2

HIDE SMILES / InChI

Molecular Formula	H3NO
Molecular Weight	33.0299
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Effect of inactivation by hydroxylamine on early functions of poliovirus.	1971 Jul	4328412
Central effects of endogenous and exogenous GABA.	1978 May-Jun	707139
Availability of dinitrophenylated lipid haptens for specific antibody binding depends on the physical properties of host bilayer membranes.	1982 Jun 10	7076676
Acute neurotoxicity of sodium azide and nitric oxide.	1991 Jul	1916070
Sulfamethoxazole is metabolized to the hydroxylamine in humans.	1992 May	1587066
Dapsone: modes of action, toxicity and possible strategies for increasing patient tolerance.	1993 Nov	8251346
Nitroxide radical biostability in skin.	1993 Oct	8225023
Reduction of dapsone hydroxylamine to dapsone during methaemoglobin formation in human erythrocytes in vitro--II. Movement of dapsone across a semipermeable membrane into erythrocytes and plasma.	1993 Oct 19	8240384
Stratum corneum intercellular lipid as compared to erythrocyte ghosts: an ESR study of thermotropic behavior and nitroxide reduction. Electron Spin Resonance.	1995	7617746
Detoxication of tyramine by the flavin-containing monooxygenase: stereoselective formation of the trans oxime.	1997 Aug	9282832
Nitric oxide ameliorates actinomycin D/endotoxin-induced apoptotic liver failure in mice.	1999 Aug	10423331
Gas chromatographic-mass spectrometric analysis of hydroxylamine for monitoring the metabolic hydrolysis of metalloprotease inhibitors in rat and human liver microsomes.	1999 Mar 5	10202971
The inhibition of human cytomegalovirus (hCMV) protease by hydroxylamine derivatives.	1999 Nov 1	10560740
Molecular diffusion into ferritin: pathways, temperature dependence, incubation time, and concentration effects.	2000 Apr	10733983
Paraquat induces different pulmonary biochemical responses in Wistar rats and Swiss mice.	2000 Mar 1	10699569
N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro.	2001 Oct	11641246
Developmental differences in the immortalization of lung fibroblasts by telomerase.	2003 Oct	14570231
NADH cytochrome b5 reductase and cytochrome b5 catalyze the microsomal reduction of xenobiotic hydroxylamines and amidoximes in humans.	2004 Dec	15302896
Identification of cytochrome P450 and arylamine N-acetyltransferase isoforms involved in sulfadiazine metabolism.	2005 Jul	15843491
Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients.	2006 May	16507648
In vitro and ex vivo activity of peptide deformylase inhibitors against Mycobacterium tuberculosis H37Rv.	2009 Sep	19505802
Individual variability in the detoxification of carcinogenic arylhydroxylamines in human breast.	2011 Jun	21447608
Bioactivation of fluorinated 2-aryl-benzothiazole antitumor molecules by human cytochrome P450s 1A1 and 2W1 and deactivation by cytochrome P450 2S1.	2012 Aug 20	22734839
Acrolein and chloroacetaldehyde: an examination of the cell and cell-free biomarkers of toxicity.	2013 Feb 25	23220588

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:24:25 GMT 2023` Edited by `admin` on `Fri Dec 15 17:24:25 GMT 2023`
Record UNII	2FP81O2L9Z
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HYDROXYLAMINE

Systematic Name

English

HYDROXYLAMINE [HSDB]

Common Name

English

HYDROXYLAMINE [MI]

Common Name

English

Code System Code Type Description

CAS

7803-49-8