Pritebegene Zepadenovec

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 20:56:35 GMT 2025` Edited by `admin` on `Wed Apr 02 20:56:35 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Adenoviridae
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	simian adenoviral Ox1 ?E1 ?E3 E4-modified ChAdOx1-HBV vector
Part	whole
Record UNII	2FFJ8WJ6EM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DNA (replication-deficient simian adenoviral Ox1 ?E1 ?E3 E4-modified ChAdOx1-HBV vector human cytomegalovirus promoter plus hepatitis B virus pre-C protein fused with core antigen fused with non-functional polymerase fused with C-terminal fragment of pre

Preferred Name

English

Pritebegene Zepadenovec

Official Name

English

replication-deficient chimpanzee adenovirus vector (ChAdOx1-?E1 ?E3 E4-modified), encoding a codon-optimized fusion protein containing multiple hepatitis B virus (HBV) antigens, comprising the HBV pre-core antigen, core antigen, a nonfunctional polymeras

Common Name

English

pritebegene zepadenovec [INN]

Common Name

English

Code System Code Type Description

CAS

2857059-64-2

Created by admin on Wed Apr 02 20:56:35 GMT 2025 , Edited by admin on Wed Apr 02 20:56:35 GMT 2025

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INN

12931

Created by admin on Wed Apr 02 20:56:35 GMT 2025 , Edited by admin on Wed Apr 02 20:56:35 GMT 2025

PRIMARY

NCI_THESAURUS

C211719

Created by admin on Wed Apr 02 20:56:35 GMT 2025 , Edited by admin on Wed Apr 02 20:56:35 GMT 2025

PRIMARY

FDA UNII

2FFJ8WJ6EM

Created by admin on Wed Apr 02 20:56:35 GMT 2025 , Edited by admin on Wed Apr 02 20:56:35 GMT 2025

PRIMARY

Related Record Type Details


					77H9EM77P7

HEPATITIS B VIRUS

TARGET ORGANISM->VACCINE ANTIGEN

Amount:


					HA3TY9EHK9

Pritebegene zepadenovec encoded preprotein antigen

EXPRESSED PROTEIN->VECTOR

Amount:

Related Record Type Details


					2FFJ8WJ6EM

Pritebegene Zepadenovec

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Fragment Name	Fragment Approval
GENE DELETION	CHIMPANZEE ADENOVIRUS E1 GENE	SK3BO0EB8B
Whole viral genome including all the modifications	Pritebegene zepadenovec whole genome	Z3BT4SSN5M
GENE DELETION	UNSPECIFIED SUBSTANCE	eb71c682 (not in database)