VATREPTACOG ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:23:08 GMT 2025` Edited by `admin` on `Mon Mar 31 21:23:08 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	2F6ZF5WYCC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VATREPTACOG ALFA (ACTIVATED)

Preferred Name

English

VATREPTACOG ALFA

Common Name

English

NN-1731

Code

English

NN1731

Code

English

VATREPTACOG ALFA (ACTIVATED) [JAN]

Common Name

English

Vatreptacog alfa (activated) [WHO-DD]

Common Name

English

vatreptacog alfa (activated) [INN]

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/12/1030

Created by admin on Mon Mar 31 21:23:08 GMT 2025 , Edited by admin on Mon Mar 31 21:23:08 GMT 2025

Code System Code Type Description

DRUG BANK

DB12409

Created by admin on Mon Mar 31 21:23:08 GMT 2025 , Edited by admin on Mon Mar 31 21:23:08 GMT 2025

PRIMARY

SMS_ID

100000177255

Created by admin on Mon Mar 31 21:23:08 GMT 2025 , Edited by admin on Mon Mar 31 21:23:08 GMT 2025

PRIMARY

FDA UNII

2F6ZF5WYCC

Created by admin on Mon Mar 31 21:23:08 GMT 2025 , Edited by admin on Mon Mar 31 21:23:08 GMT 2025

PRIMARY

NCI_THESAURUS

C152841

Created by admin on Mon Mar 31 21:23:08 GMT 2025 , Edited by admin on Mon Mar 31 21:23:08 GMT 2025

PRIMARY

CAS

897936-89-9

Created by admin on Mon Mar 31 21:23:08 GMT 2025 , Edited by admin on Mon Mar 31 21:23:08 GMT 2025

PRIMARY

ChEMBL

CHEMBL2108322

Created by admin on Mon Mar 31 21:23:08 GMT 2025 , Edited by admin on Mon Mar 31 21:23:08 GMT 2025

PRIMARY

INN

8844

Created by admin on Mon Mar 31 21:23:08 GMT 2025 , Edited by admin on Mon Mar 31 21:23:08 GMT 2025

PRIMARY

From	To
1_7	1_12
1_26	1_42
1_158	1_177
1_188	1_216
2_17	2_22
2_50	2_61
2_55	2_70
2_72	2_81
2_91	2_102
2_98	2_112
2_114	2_127
1_110	2_135

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_170
N	2_145
O	2_52
O	2_60

Related Record Type Details


					2F6ZF5WYCC

VATREPTACOG ALFA

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
ENZYMATIC 3R-HYDROXYLATION	[2_63]	SITE_SPECIFIC	ASP		.BETA.-HYDROXY-L-ASPARTIC ACID, ERYTHRO-	GDV0MSK2SG
ENZYMATIC GAMMA-CARBOXYLATION	[2_6] [2_7] [2_14] [2_16] [2_19] [2_20] [2_25] [2_26] [2_29] [2_35]	SITE_SPECIFIC	GLU		.GAMMA.-CARBOXYGLUTAMIC ACID	16FQV4RZKL

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(ESTIMATED)	CHEMICAL
Molecular Formula	CHEMICAL