AZAMIDUGENE AUTOTEMCEL VECTOR

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 18:57:26 GMT 2023` Edited by `admin` on `Sat Dec 16 18:57:26 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	SELF-INACTIVATING
Organism Family	Retroviridae
Organism Genus	Lentivirus
Organism Species	human immunodeficiency virus 1
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	Self-inactivating LV-PGK promoter-alpha-L-iduronidase (IDUA)
Part	whole
Record UNII	2CX3CU3LQY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AZAMIDUGENE AUTOTEMCEL VECTOR

Common Name

English

SELF-INACTIVATING LENTIVIRAL VECTOR EXPRESSING HUMAN ALPHA-L-IDURONIDASE (IDUA) UNDER THE CONTROL OF A HUMAN PHOSPHOGLYCERATE KINASE (PGK)PROMOTER THE CONSTRUCT IS FLANKED BY 5' AND 3' LONG TERMINAL REPEATS (LTRS) AND ALSO CONTAINS A HIV-1 .PSI. PACKAGIN

Common Name

English

Code System Code Type Description

FDA UNII

2CX3CU3LQY

Created by admin on Sat Dec 16 18:57:26 GMT 2023 , Edited by admin on Sat Dec 16 18:57:26 GMT 2023

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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
GENE_EXPRESSION VECTOR					AZAMIDUGENE AUTOTEMCEL TRANSGENE INSERT	65HBD4H5PV