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Details

Stereochemistry ACHIRAL
Molecular Formula C9H9NO
Molecular Weight 147.1739
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROCARBOSTYRIL

SMILES

O=C1CCC2=CC=CC=C2N1

InChI

InChIKey=TZOYXRMEFDYWDQ-UHFFFAOYSA-N
InChI=1S/C9H9NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-4H,5-6H2,(H,10,11)

HIDE SMILES / InChI

Molecular Formula C9H9NO
Molecular Weight 147.1739
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia.
2010-05-01
Ethyl 6-chloro-2-oxo-4-phenyl-1,2-dihydro-quinoline-3-carboxyl-ate.
2009-11-04
Synthesis of highly enantioenriched 3,4-dihydroquinolin-2-ones by 6-exo-trig radical cyclizations of axially chiral alpha-halo-ortho-alkenyl anilides.
2009-10-28
(RS)-3-Acetyl-2-methyl-4-(3-nitro-phen-yl)-1,4,5,6,7,8-hexa-hydro-quinolin-5-one.
2009-09-26
Novel approach to 3,4-dihydro-2(1H)-quinolinone derivatives via cyclopropane ring expansion.
2009-03-05
In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.
2008-12-25
Comparison of the bioactivation potential of the antidepressant and hepatotoxin nefazodone with aripiprazole, a structural analog and marketed drug.
2008-06
Synthesis and biological activity of quinolinone and dihydroquinolinone p38 MAP kinase inhibitors.
2008-03-15
Quinoline and derivatives at a tar oil contaminated site: hydroxylated products as indicator for natural attenuation?
2007-08-01
Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors.
2007-01-15
Synthesis and SAR of highly potent and selective dopamine D(3)-receptor antagonists: Quinolin(di)one and benzazepin(di)one derivatives. herve.geneste@abbott.com.
2006-02
Synthesis of five-, six-, and seven-membered ring lactams by CpRh complex-catalyzed oxidative N-heterocyclization of amino alcohols.
2004-08-05
Novel 3,4-dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a.
2003-12-15
Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter: Part 3. A potential 5-HT transporter imaging agent, 3-(3-[18F]fluoropropyl)-6-nitroquipazine.
2003-11-17
Radical ring closures of 4-isocyanato carbon-centered radicals.
2003-04-04
Synthesis and vasorelaxing evaluation of alpha-methylidene-gamma-butyrolactone bearing quinolin-2(1H)-one and 3,4-dihydroquinolin-2(1H)-one derivatives.
2002-01-05
Synthesis of 3-methoxycarbonylmethyl derivatives of dihydroquinolone and dihydrochromenone.
2001-03-23
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:22:18 GMT 2025
Edited
by admin
on Mon Mar 31 21:22:18 GMT 2025
Record UNII
2CKG6TX32F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HYDROCARBOSTYRIL
MI  
Common Name English
NSC-49170
Preferred Name English
1,2,3,4-TETRAHYDRO-2(1H)-QUINOLINONE
Common Name English
1,2,3,4-TETRAHYDROQUINOLIN-2-ONE
Systematic Name English
3,4-DIHYDRO-2(1H)-QUINOLINONE
Systematic Name English
3,4-DIHYDROQUINOLIN-2(1H)-ONE
Systematic Name English
3,4-DIHYDROCARBOSTYRIL
Common Name English
3,4-DIHYDRO-2(1H)-QUINOLONE
Systematic Name English
3,4-DIHYDRO-2-QUINOLINONE
Systematic Name English
3,4-DIHYDRO-2-QUINOLINOL
Systematic Name English
1,2,3,4-TETRAHYDRO-2-OXOQUINOLINE
Systematic Name English
3,4-DIHYDRO-1H-QUINOLIN-2-ONE
Systematic Name English
O-AMINOHYDROCINNAMIC ACID LACTAM
Common Name English
2-OXO-1,2,3,4-TETRAHYDROQUINOLINE
Systematic Name English
3,4-DIHYDRO-2-QUINOLONE
Systematic Name English
HYDROCARBOSTYRIL [MI]
Common Name English
Code System Code Type Description
MERCK INDEX
m6087
Created by admin on Mon Mar 31 21:22:18 GMT 2025 , Edited by admin on Mon Mar 31 21:22:18 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID40203816
Created by admin on Mon Mar 31 21:22:18 GMT 2025 , Edited by admin on Mon Mar 31 21:22:18 GMT 2025
PRIMARY
FDA UNII
2CKG6TX32F
Created by admin on Mon Mar 31 21:22:18 GMT 2025 , Edited by admin on Mon Mar 31 21:22:18 GMT 2025
PRIMARY
PUBCHEM
64796
Created by admin on Mon Mar 31 21:22:18 GMT 2025 , Edited by admin on Mon Mar 31 21:22:18 GMT 2025
PRIMARY
CAS
553-03-7
Created by admin on Mon Mar 31 21:22:18 GMT 2025 , Edited by admin on Mon Mar 31 21:22:18 GMT 2025
PRIMARY
NSC
49170
Created by admin on Mon Mar 31 21:22:18 GMT 2025 , Edited by admin on Mon Mar 31 21:22:18 GMT 2025
PRIMARY