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Details

Stereochemistry ACHIRAL
Molecular Formula C3Cl6O3
Molecular Weight 296.748
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIPHOSGENE

SMILES

ClC(Cl)(Cl)OC(=O)OC(Cl)(Cl)Cl

InChI

InChIKey=UCPYLLCMEDAXFR-UHFFFAOYSA-N
InChI=1S/C3Cl6O3/c4-2(5,6)11-1(10)12-3(7,8)9

HIDE SMILES / InChI

Molecular Formula C3Cl6O3
Molecular Weight 296.748
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.
2010-09-14
Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.
2010-04-30
6-Chloro-8-methyl-4H-3,1-benzoxazine-2,4(1H)-dione.
2010-04-21
Solid phase synthesis of hydrogen bond surrogate derived alpha-helices: resolving the case of a difficult amide coupling.
2010-04-21
Inhibitors of N(alpha)-acetyl-L-ornithine deacetylase: synthesis, characterization and analysis of their inhibitory potency.
2010-04
catena-Poly[[[triaqua-sulfatozinc(II)]-μ-3,3'-bis-(3-pyrid-yl)-1,1'-(m-phenyl-ene)diurea] methanol solvate monohydrate].
2010-03-17
Synthesis of 1,3-azaphosphol-2-ones. Crystal and molecular structures of [SP-4-2]-dichlorobis(3-phenyl-1,3-dihydrobenzo[1,3]azaphosphol-2-one-P)palladium(II) and its chloro(methyl)platinum(II) analogue.
2010-01-07
Novel synthesis of N-alkoxycarbonyl amino acids and surfactant properties of their sodium salts.
2010
Oriented synthesis and in vitro anticancer activity of biquinazoline-2,2'-diones.
2009-12-24
Simple, rapid, and highly sensitive detection of diphosgene and triphosgene by spectrophotometric methods.
2009-11-15
Efficient synthesis of naphtho[1,2-e][1,3]oxazine derivatives via a chemoselective reaction with the aid of low-valent titanium reagent.
2009-10-30
Highly efficient synthesis of DNA-binding hairpin polyamides via the use of a new triphosgene coupling strategy.
2009-09-03
Synthesis of 3-N-sugar-substituted-2, 4(1H,3H)-quinazolinedionesas anti-angiogenesis agents.
2009-07-08
Cyclization of hydrazones of 2-acetyl-1-naphthol and 1-acetyl-2-naphthol with triphosgene. Synthesis of Spiro naphthoxazine dimers.
2009-06-12
The Amadori rearrangement as key reaction for the synthesis of neoglycoconjugates.
2008-08-11
Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain.
2008-08-01
Synthesis and biological evaluation of a novel pentagastrin-toxin conjugate designed for a targeted prodrug mono-therapy of cancer.
2008-05
Pharmacokinetic characteristics and anticancer effects of 5-fluorouracil loaded nanoparticles.
2008-04-15
Synthesis and in silico biological activity evaluation of new N-substituted pyrazolo-oxazin-2-one systems.
2008-03-15
Gold(I) chloride adducts of 1,3-bis(di-2-pyridylphosphino)propane: synthesis, structural studies and antitumour activity.
2007-11-21
Peptide immobilization on amine-terminated boron-doped diamond surfaces.
2007-04-10
A FRET approach to phosgene detection.
2007-03-28
First catalytic and green synthesis of aryl-(Z)-vinyl chlorides and its plausible addition-elimination mechanism.
2007-03-15
[Emergency treatment and nursing for patients with acute triphosgene poisoning].
2007-03
Synthesis and antimicrobial activity of new (4,4,4-trihalo-3-oxo-but-1-enyl)-carbamic acid ethyl esters, (4,4,4-trihalo-3-hydroxy-butyl)-carbamic acid ethyl esters, and 2-oxo-6-trihalomethyl-[1,3]oxazinane-3-carboxylic acid ethyl esters.
2006-05-01
Synthesis of hydantoins from enantiomerically pure alpha-amino amides without epimerization.
2006-02-17
Peptide crosslinked micelles: a new strategy for the design and synthesis of peptide vaccines.
2006
Deazapurine solid-phase synthesis: combinatorial synthesis of a library of N3,N5,C6-trisubstituted pyrrolo[3,2-d]pyrimidine derivatives on cross-linked polystyrene bearing a cysteamine linker.
2005-11-15
Functional analysis of backbone cyclic peptides bearing the arm domain of the HIV-1 Rev protein: characterization of the karyophilic properties and inhibition of Rev-induced gene expression.
2005-08-30
Development of an efficient strategy for the synthesis of the ETB receptor antagonist BQ-788 and some related analogues.
2005-08
Synthesis of disubstituted imidazo[4,5-b]pyridin-2-ones.
2004-10-29
Novel fluoro- and hydroxyl-containing jasmonate derivatives as highly efficient elicitors in suspension cultures of Taxus chinensis.
2004-09-20
The use of solid-phase supported 1-N-piperazine-4-N-carboxaldehyde in Vilsmeier reactions.
2004-03-09
Parallel solid-phase synthesis of disubstituted (5-biphenyltetrazolyl) hydantoins and thiohydantoins targeting the growth hormone secretagogue receptor.
2004-01-19
Debenzylation of tertiary amines using phosgene or triphosgene: an efficient and rapid procedure for the preparation of carbamoyl chlorides and unsymmetrical ureas. Application in carbon-11 chemistry.
2003-09-19
Selective cleavage of N-benzyl-protected secondary amines by triphosgene.
2003-01-24
Unexpected formation of an azetidine-carborane derivative by dehydration of N-(1,12-dicarba-closo-dodecaboran-1-yl)formamide. The first X-ray structure of a 2,3-bis(imino)azetidine.
2002-12-02
Complexation-induced unfolding of heterocyclic ureas. Simple foldamers equilibrate with multiply hydrogen-bonded sheetlike structures.
2001-10-31
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:15:31 GMT 2025
Edited
by admin
on Mon Mar 31 21:15:31 GMT 2025
Record UNII
2C0677Q3B2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRIPHOSGENE
MI  
Systematic Name English
1,1,1-TRICHLOROMETHANOL 1,1'-CARBONATE
Preferred Name English
TRIPHOSGENE [MI]
Common Name English
HEXACHLORODIMETHYL CARBONATE
Common Name English
TRICHLOROMETHYL CARBONATE
Systematic Name English
BTC
Common Name English
CARBONIC ACID, BIS(TRICHLOROMETHYL) ESTER
Common Name English
BIS(TRICHLOROMETHYL) CARBONATE
Systematic Name English
METHANOL, TRICHLORO-, CARBONATE (2:1)
Systematic Name English
Code System Code Type Description
WIKIPEDIA
TRIPHOSGENE
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY
MERCK INDEX
m11191
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY Merck Index
SMS_ID
100000164210
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY
FDA UNII
2C0677Q3B2
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY
PUBCHEM
94429
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY
EVMPD
SUB178573
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY
CAS
32315-10-9
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY
ECHA (EC/EINECS)
250-986-3
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY
EPA CompTox
DTXSID00865631
Created by admin on Mon Mar 31 21:15:31 GMT 2025 , Edited by admin on Mon Mar 31 21:15:31 GMT 2025
PRIMARY