U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Tue Apr 01 22:45:48 GMT 2025
Edited
by admin
on Tue Apr 01 22:45:48 GMT 2025
Nucleic Acid Type OLIGONUCLEOTIDE
Sequence Type COMPLETE
Record UNII
29B884400A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EIF-4E ASO
Common Name English
EIF-4E ANTISENSE OLIGONUCLEOTIDE
Preferred Name English
Code System Code Type Description
FDA UNII
29B884400A
Created by admin on Tue Apr 01 22:45:48 GMT 2025 , Edited by admin on Tue Apr 01 22:45:48 GMT 2025
PRIMARY
Sugar Site Range Site Count
2'-O-Methoxyethyl ribose 1_1-1_5;1_16-1_20 10 / 20
Deoxyribose (DNA) 1_6-1_15 10 / 20
Linkage Site Range Site Count
Sodium Phosporothioate 1_2-1_20 19 / 19

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOSIDE_SUBSTITUTION [1_10] [1_11] 5-METHYLCYTIDINE TL9PB228DC
NUCLEOSIDE_SUBSTITUTION [1_17] [1_18] 2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE AOQ54IZZ6J