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Details

Stereochemistry ACHIRAL
Molecular Formula C22H24O9
Molecular Weight 432.4206
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 3,5,6,7,8,3',4'-HEPTAMETHPHOXYFLAVONE

SMILES

COC1=CC=C(C=C1OC)C2=C(OC)C(=O)C3=C(O2)C(OC)=C(OC)C(OC)=C3OC

InChI

InChIKey=SSXJHQZOHUYEGD-UHFFFAOYSA-N
InChI=1S/C22H24O9/c1-24-12-9-8-11(10-13(12)25-2)16-19(27-4)15(23)14-17(26-3)20(28-5)22(30-7)21(29-6)18(14)31-16/h8-10H,1-7H3

HIDE SMILES / InChI

Molecular Formula C22H24O9
Molecular Weight 432.4206
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Cancer chemopreventive activity of 3,5,6,7,8,3',4'-heptamethoxyflavone from the peel of citrus plants.
2001 Feb 10
Immunotoxicity of a standardized citrus polymethoxylated flavone extract.
2001 Nov
Fungicidal potential of methoxylated flavones from citrus for in vitro control of Colletotrichum gloeosporioides, causal agent of anthracnose disease in tropical fruits.
2003 Nov
Preparative isolation and purification of polymethoxylated flavones from Tangerine peel using high-speed counter-current chromatography.
2005 Oct 7
Efficient and scalable method in isolation of polymethoxyflavones from orange peel extract by supercritical fluid chromatography.
2007 Feb 1
A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells.
2008 Feb 1
Validated reversed phase LC method for quantitative analysis of polymethoxyflavones in citrus peel extracts.
2008 Jan
Simultaneous determination of five bioactive flavonoids in pericarpium Citri reticulatae from china by high-performance liquid chromatography with dual wavelength detection.
2009 Aug 12
Polymethoxyflavones activate Ca2+-dependent apoptotic targets in adipocytes.
2009 Jul 8
Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis.
2009 Mar
Flavonoids from the stems of Croton caudatus Geisel. var. tomentosus Hook.
2010 Feb 26
Isolation and identification of polymethoxyflavones from the hybrid Citrus, hallabong.
2010 Sep 8
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:47:58 GMT 2023
Edited
by admin
on Fri Dec 15 18:47:58 GMT 2023
Record UNII
288R4CAV1V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
3,5,6,7,8,3',4'-HEPTAMETHPHOXYFLAVONE
Systematic Name English
3-METHOXYNOBILETIN
Common Name English
3',4',3,5,6,7,8-HEPTAMETHOXYFLAVONE
Systematic Name English
FLAVONE, 3,3',4',5,6,7,8-HEPTAMETHOXY-
Systematic Name English
4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIMETHOXYPHENYL)-3,5,6,7,8-PENTAMETHOXY-
Systematic Name English
3,5,6,7,8,3',4'-HEPTAMETHOXYFLAVONE
Official Name English
2-(3,4-DIMETHOXYPHENYL)-3,5,6,7,8-PENTAMETHOXY-4H-1-BENZOPYRAN-4-ONE
Systematic Name English
3,3',4',5,6,7,8-HEPTAMETHOXYFLAVONE
Systematic Name English
NSC-618928
Code English
Code System Code Type Description
FDA UNII
288R4CAV1V
Created by admin on Fri Dec 15 18:47:58 GMT 2023 , Edited by admin on Fri Dec 15 18:47:58 GMT 2023
PRIMARY
CAS
1178-24-1
Created by admin on Fri Dec 15 18:47:58 GMT 2023 , Edited by admin on Fri Dec 15 18:47:58 GMT 2023
PRIMARY
PUBCHEM
150893
Created by admin on Fri Dec 15 18:47:58 GMT 2023 , Edited by admin on Fri Dec 15 18:47:58 GMT 2023
PRIMARY
EPA CompTox
DTXSID70151912
Created by admin on Fri Dec 15 18:47:58 GMT 2023 , Edited by admin on Fri Dec 15 18:47:58 GMT 2023
PRIMARY
NSC
618928
Created by admin on Fri Dec 15 18:47:58 GMT 2023 , Edited by admin on Fri Dec 15 18:47:58 GMT 2023
PRIMARY
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