Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H24O9 |
| Molecular Weight | 432.4206 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C(C=C1OC)C2=C(OC)C(=O)C3=C(O2)C(OC)=C(OC)C(OC)=C3OC
InChI
InChIKey=SSXJHQZOHUYEGD-UHFFFAOYSA-N
InChI=1S/C22H24O9/c1-24-12-9-8-11(10-13(12)25-2)16-19(27-4)15(23)14-17(26-3)20(28-5)22(30-7)21(29-6)18(14)31-16/h8-10H,1-7H3
| Molecular Formula | C22H24O9 |
| Molecular Weight | 432.4206 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Isolation and identification of polymethoxyflavones from the hybrid Citrus, hallabong. | 2010-09-08 |
|
| Flavonoids from the stems of Croton caudatus Geisel. var. tomentosus Hook. | 2010-02-26 |
|
| Simultaneous determination of five bioactive flavonoids in pericarpium Citri reticulatae from china by high-performance liquid chromatography with dual wavelength detection. | 2009-08-12 |
|
| Polymethoxyflavones activate Ca2+-dependent apoptotic targets in adipocytes. | 2009-07-08 |
|
| Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis. | 2009-03 |
|
| Anti-inflammatory activity of an orange peel polymethoxylated flavone, 3',4',3,5,6,7,8-heptamethoxyflavone, in the rat carrageenan/paw edema and mouse lipopolysaccharide-challenge assays. | 2008-10-22 |
|
| A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells. | 2008-02-01 |
|
| Validated reversed phase LC method for quantitative analysis of polymethoxyflavones in citrus peel extracts. | 2008-01 |
|
| Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells. | 2007-10 |
|
| Efficient and scalable method in isolation of polymethoxyflavones from orange peel extract by supercritical fluid chromatography. | 2007-02-01 |
|
| Preparative isolation and purification of polymethoxylated flavones from Tangerine peel using high-speed counter-current chromatography. | 2005-10-07 |
|
| Effect of flavones on rat brain and lung matrix metalloproteinase activity measured by film in-situ zymography. | 2005-04 |
|
| [Chemical study of citrus plants in the search for cancer chemopreventive agents]. | 2005-03 |
|
| Topochemical model for prediction of anti-HIV activity of HEPT analogs. | 2005-01-17 |
|
| Fungicidal potential of methoxylated flavones from citrus for in vitro control of Colletotrichum gloeosporioides, causal agent of anthracnose disease in tropical fruits. | 2003-11 |
|
| Identification of epoxybergamottin as a CYP3A4 inhibitor in grapefruit peel. | 2003-02 |
|
| Genetic toxicity of a standardized mixture of citrus polymethoxylated flavones. | 2002-05 |
|
| Immunotoxicity of a standardized citrus polymethoxylated flavone extract. | 2001-11 |
|
| Cancer chemopreventive activity of 3,5,6,7,8,3',4'-heptamethoxyflavone from the peel of citrus plants. | 2001-02-10 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:21:20 GMT 2025
by
admin
on
Mon Mar 31 19:21:20 GMT 2025
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| Record UNII |
288R4CAV1V
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| Record Status |
Validated (UNII)
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| Record Version |
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288R4CAV1V
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1178-24-1
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150893
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DTXSID70151912
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618928
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