U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Thu Jul 06 19:23:43 UTC 2023
Edited
by admin
on Thu Jul 06 19:23:43 UTC 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
27TW751DTH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ASTEGOLIMAB
USAN   INN  
Official Name English
MSTT1041A
Code English
IMMUNOGLOBULIN G2, ANTI-(HUMAN INTERLEUKIN-33 RECEPTOR) (HUMAN MONOCLONAL MSTT1041A .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MSTT1041A .KAPPA.-CHAIN, DIMER
Common Name English
RG6149
Code English
AMG282
Code English
AMG-282
Code English
RG-6149
Code English
MSTT-1041A
Code English
IMMUNOGLOBULIN GX-KAPPA, ANTI-(HOMO SAPIENS INTERLEUKIN-1 RECEPTOR-LIKE 1 (PROTEIN ST2, EC=3.2.2.6)) HOMO SAPIENS MONOCLONAL ANTIBODY.GAMMA.2 HEAVY CHAIN HOMO SAPIENS (1-447) (HOMO SAPIENS VH (IGHV5-51*01 (96%) (IGHD)-IGHJ6*01 (94%)) (8.8.14) (1-121)-HOM
Common Name English
RO-7187807
Code English
ASTEGOLIMAB [USAN]
Common Name English
astegolimab [INN]
Common Name English
HUMAN MAB THAT INHIBITS THE BINDING OF IL-33 (NF-HEV) TO IL-1 RECEPTOR-LIKE 1
Common Name English
Astegolimab [WHO-DD]
Common Name English
Code System Code Type Description
INN
11067
Created by admin on Thu Jul 06 19:23:43 UTC 2023 , Edited by admin on Thu Jul 06 19:23:43 UTC 2023
PRIMARY
CAS
2173054-79-8
Created by admin on Thu Jul 06 19:23:43 UTC 2023 , Edited by admin on Thu Jul 06 19:23:43 UTC 2023
PRIMARY
USAN
HI-116
Created by admin on Thu Jul 06 19:23:43 UTC 2023 , Edited by admin on Thu Jul 06 19:23:43 UTC 2023
PRIMARY
NCI_THESAURUS
C171824
Created by admin on Thu Jul 06 19:23:43 UTC 2023 , Edited by admin on Thu Jul 06 19:23:43 UTC 2023
PRIMARY
FDA UNII
27TW751DTH
Created by admin on Thu Jul 06 19:23:43 UTC 2023 , Edited by admin on Thu Jul 06 19:23:43 UTC 2023
PRIMARY
From To
1_22 1_96
1_135 3_214
1_148 1_204
1_223 2_223
1_224 2_224
1_227 2_227
1_230 2_230
1_261 1_321
1_367 1_425
2_22 2_96
2_135 4_214
2_148 2_204
2_261 2_321
2_367 2_425
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
TARGET -> INHIBITOR
anti-ST2 human IgG2κ monoclonal antibody that blocks IL-33 binding to IL-1 family receptor ST2
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL