LJH-685

CN1CCN(CC1)C2=CC=C(C=C2)C3=C(C=NC=C3)C4=CC(F)=C(O)C(F)=C4

InChIKey=IKUFKDGKRLMXEX-UHFFFAOYSA-N

InChI=1S/C22H21F2N3O/c1-26-8-10-27(11-9-26)17-4-2-15(3-5-17)18-6-7-25-14-19(18)16-12-20(23)22(28)21(24)13-16/h2-7,12-14,28H,8-11H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Ribosomal protein S6 kinase alpha-1 1 Target ID: Q15418\|\|\|Q5SVM9 Gene ID: 6195.0 Gene Symbol: RPS6KA1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/24554780	Inhibitor 8297	6.0 nM [IC50]
Ribosomal protein S6 kinase alpha-3 2 Target ID: P51812 Gene ID: 6197.0 Gene Symbol: RPS6KA3 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/24554780	Inhibitor 8297	5.0 nM [IC50]
Ribosomal protein S6 kinase alpha-2 1 Target ID: Q15349 Gene ID: 6196.0 Gene Symbol: RPS6KA2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/24554780	Inhibitor 8297	4.0 nM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:18:42 GMT 2023` Edited by `admin` on `Sat Dec 16 05:18:42 GMT 2023`
Record UNII	27CZQ807C1
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

LJH-685

Common Name

English

LJH685

Code

English

PHENOL, 2,6-DIFLUORO-4-(4-(4-(4-METHYL-1-PIPERAZINYL)PHENYL)-3-PYRIDINYL)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

73010393

Created by admin on Sat Dec 16 05:18:42 GMT 2023 , Edited by admin on Sat Dec 16 05:18:42 GMT 2023

PRIMARY

CAS

1627710-50-2

Created by admin on Sat Dec 16 05:18:42 GMT 2023 , Edited by admin on Sat Dec 16 05:18:42 GMT 2023

PRIMARY

FDA UNII

27CZQ807C1

Created by admin on Sat Dec 16 05:18:42 GMT 2023 , Edited by admin on Sat Dec 16 05:18:42 GMT 2023

PRIMARY