DI-TERT-BUTYLHYDROQUINONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H22O2
Molecular Weight	222.3233
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)C1=CC(O)=C(C=C1O)C(C)(C)C

InChI

InChIKey=JZODKRWQWUWGCD-UHFFFAOYSA-N

InChI=1S/C14H22O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8,15-16H,1-6H3

HIDE SMILES / InChI

Molecular Formula	C14H22O2
Molecular Weight	222.3233
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Human respiratory syncytial virus 1 Target ID: CHEMBL613127 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27210812	Inhibitor 8297
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Target ID: Sarcoplasmic/endoplasmic reticulum calcium ATPase Sources: https://www.ncbi.nlm.nih.gov/pubmed/16691466	Inhibitor 8297

PubMed

Title	Date	PubMed
Ionomycin and 2,5'-di(tertbutyl)-1,4,-benzohydroquinone elicit Ca2+-induced Ca2+ release from intracellular pools in Physarum polycephalum.	2001 Feb	11223389
Ca(2+) entry into primary cultured pig coronary smooth muscle cells after previous store depletion by repetitive P2Y purinoceptor stimulation.	2001 May	11292392
[Cytokine and chemokine gene expressions as makers of chemically induced allergies].	2003	14977016
Calcium ions as a factor of cell-cell cooperation in hepatocyte cultures.	2003	14642528
Calcium signaling to nucleus via store-operated system during cell cycle in retinal neuroepithelium.	2003 Apr	12657458
Evaluation, using targeted aequorins, of the roles of the endoplasmic reticulum and its (Ca2++Mg2+)ATP-ases in the activation of store-operated Ca2+ channels in liver cells.	2004 Apr	15036949
Contribution of store-operated Ca2+ entry to pHo-dependent changes in vascular tone of porcine coronary smooth muscle.	2004 Jan	14670367
Regulation and identity of intracellular calcium stores involved in membrane cross talk in the early distal tubule of the frog kidney.	2004 Jun	15053990
Induction of cholestasis in the perfused rat liver by 2-aminoethyl diphenylborate, an inhibitor of the hepatocyte plasma membrane Ca2+ channels.	2004 Oct	15377289
Studies of Ca2+ ATPase (SERCA) inhibition.	2005 Dec	16691466
A role for ERK1/2 in EGF- and ATP-dependent regulation of amiloride-sensitive sodium absorption.	2005 May	15634742
Effect of ADP on slow-twitch muscle fibres of the rat: implications for muscle fatigue.	2006 May 15	16556653
Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum.	2006 May 15	16466345
In silico elucidation of the molecular mechanism defining the adverse effect of selective estrogen receptor modulators.	2007 Nov	18052534
[Modulation of electrical responses of endothelial cells by nicotinic cholinoreceptors].	2009	19526844
Design, synthesis, and biological evaluation of hydroquinone derivatives as novel inhibitors of the sarco/endoplasmic reticulum calcium ATPase.	2009 Sep 15	19699645
Uncoupling protein 3 adjusts mitochondrial Ca(2+) uptake to high and low Ca(2+) signals.	2010 Nov	21047682

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:01:38 GMT 2023` Edited by `admin` on `Fri Dec 15 18:01:38 GMT 2023`
Record UNII	26XK13B61B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DI-TERT-BUTYLHYDROQUINONE

Systematic Name

English

BUTYLHYDROQUINONE, 2,5-DI-TERT-

Systematic Name

English

HYDROQUINONE, 2,5-DI-TERT-BUTYL-

Systematic Name

English

2,5-DI-TERT-BUTYL-1,4-BENZOHYDROQUINONE

Common Name

English

2,5-DI-TERT-BUTYL-1,4-HYDROQUINONE

Common Name

English

NSC-11

Code

English

2,5-DI-TERT-BUTYLBENZENE-1,4-DIOL

Systematic Name

English

DI-T-BUTYLHYDROQUINONE [INCI]

Common Name

English

1,4-DIHYDROXY-2,5-DI-TERT-BUTYLBENZENE

Systematic Name

English

1,4-BENZENEDIOL, 2,5-BIS(1,1-DIMETHYLETHYL)-

Systematic Name

English

2,5-DI-TERT-BUTYLHYDROQUINONE

Systematic Name

English

DI-T-BUTYLHYDROQUINONE

Official Name

English

NAUGARD 451

Brand Name

English

2,5-DI-TERT-BUTYL HYDROQUINONE

Systematic Name

English

2,5-DI-TERT-BUTYL-1,4-BENZENEDIOL

Systematic Name

English

2,5-DI-TERT-BUTYLQUINOL

Systematic Name

English

Classification Tree Code System Code

CFR

21 CFR 176.170