METHADONE HYDROBROMIDE, (R)-

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H27NO.BrH
Molecular Weight	390.357
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of METHADONE HYDROBROMIDE, (R)-

Structure Search

SMILES

Br.CCC(=O)C(C[C@@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=FSICAXDYXLRLRG-UNTBIKODSA-N

InChI=1S/C21H27NO.BrH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H/t17-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C21H27NO
Molecular Weight	309.4452
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: Helmut Buschmann (20 December 2002). Analgesics: From Chemistry and Pharmacology to Clinical Application. Wiley-VCH. p. 196. ISBN 978-3-527-30403-5. | F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1294. ISBN 978-0-412-46630-4.
Curator's Comment: see METHADONE

levomethadone, or R-(−)-methadone, is the active enantiomer of methadone; having approximately 50x the potency of the S-(+)-enantiomer as well as greater μ-opioid receptor selectivity.

CNS Activity

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
In silico prediction of pregnane X receptor activators by machine learning approaches.	2007 Jan	17003167

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:45:01 GMT 2023` Edited by `admin` on `Sat Dec 16 18:45:01 GMT 2023`
Record UNII	26HS5V5X8R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METHADONE HYDROBROMIDE, (R)-

Common Name

English

(R)-(-)-METHADONE HYDROBROMIDE

Common Name

English

L-METHADONE HYDROBROMIDE

Common Name

English

3-HEPTANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, HYDROBROMIDE, (R)-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID70941532

Created by admin on Sat Dec 16 18:45:01 GMT 2023 , Edited by admin on Sat Dec 16 18:45:01 GMT 2023

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FDA UNII

26HS5V5X8R

Created by admin on Sat Dec 16 18:45:01 GMT 2023 , Edited by admin on Sat Dec 16 18:45:01 GMT 2023

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PUBCHEM

20055404

Created by admin on Sat Dec 16 18:45:01 GMT 2023 , Edited by admin on Sat Dec 16 18:45:01 GMT 2023

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CAS

19767-48-7

Created by admin on Sat Dec 16 18:45:01 GMT 2023 , Edited by admin on Sat Dec 16 18:45:01 GMT 2023

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