IMINODIBENZYL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H13N
Molecular Weight	195.2597
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1CC2=C(NC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=ZSMRRZONCYIFNB-UHFFFAOYSA-N

InChI=1S/C14H13N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-8,15H,9-10H2

HIDE SMILES / InChI

Molecular Formula	C14H13N
Molecular Weight	195.2597
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20804147 | https://www.ncbi.nlm.nih.gov/pubmed/25525363 | https://www.ncbi.nlm.nih.gov/pubmed/14050414 | https://www.ncbi.nlm.nih.gov/pubmed/28414928 | https://www.ncbi.nlm.nih.gov/pubmed/19686697

Iminodibenzyl is an impurity in commercial preparations of Carbamazepine. It is the final product of antidepressant imipramine oxidation. Iminodibenzyl is a building block of many antipsychotic drugs. Iminodibenzyl derivatives demonstrated anti-leishmanial activity. Iminodibenzyl, in combination with 3-methyl-2-benzothiazolinonehydrazone hydrochloride are used as chromogenic co-substrates for quantification of hydrogen peroxide and glucose.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Quantification of hydrogen peroxide and glucose using 3-methyl-2-benzothiazolinonehydrazone hydrochloride with 10,11-dihydro-5H-benz(b,f)azepine as chromogenic probe.	2009 Dec 15	19686697
In vitro studies of DNA damage caused by tricyclic antidepressants: a role of peroxidase in the side effects of the drugs.	2010 Sep 20	20804147
Iminodibenzyl class antipsychotics for schizophrenia: a systematic review and meta-analysis of carpipramine, clocapramine, and mosapramine.	2014	25525363
New iminodibenzyl derivatives with anti-leishmanial activity.	2017 Jul	28414928

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:45:08 UTC 2023` Edited by `admin` on `Fri Dec 15 15:45:08 UTC 2023`
Record UNII	262BX7OE3U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IMINODIBENZYL

Common Name

English

10,11-DIHYDRODIBENZ(B,F)AZEPINE

Systematic Name

English

5H-DIBENZ(B,F)AZEPINE, 10,11-DIHYDRO-

Systematic Name

English

CARBAMAZEPINE IMPURITY E [IP]

Common Name

English

10,11-DIHYDRO-5H-DIBENZ(B.F)AZEPINE

Systematic Name

English

IMINODIBENZYL TRIMIPRAMINE [USP IMPURITY]

Common Name

English

10,11-DIHYDRO-5H-DIBENZO(B,F)AZEPINE

Systematic Name

English

CLOMIPRAMINE HYDROCHLORIDE IMPURITY E [EP IMPURITY]

Common Name

English

2,2'-IMINOBIBENZYL

Common Name

English

2,2'-IMINODIBENZYL

Common Name

English

IMINOBIBENZYL

Systematic Name

English

TRIMIPRAMINE MALEATE IMPURITY F [EP IMPURITY]

Common Name

English

CARBAMAZEPINE IMPURITY E [EP IMPURITY]

Common Name

English

NSC-72110

Code

English

Code System Code Type Description

FDA UNII

262BX7OE3U