IMINODIBENZYL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H13N
Molecular Weight	195.2597
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1CC2=C(NC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=ZSMRRZONCYIFNB-UHFFFAOYSA-N

InChI=1S/C14H13N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-8,15H,9-10H2

HIDE SMILES / InChI

Molecular Formula	C14H13N
Molecular Weight	195.2597
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20804147 | https://www.ncbi.nlm.nih.gov/pubmed/25525363 | https://www.ncbi.nlm.nih.gov/pubmed/14050414 | https://www.ncbi.nlm.nih.gov/pubmed/28414928 | https://www.ncbi.nlm.nih.gov/pubmed/19686697

Iminodibenzyl is an impurity in commercial preparations of Carbamazepine. It is the final product of antidepressant imipramine oxidation. Iminodibenzyl is a building block of many antipsychotic drugs. Iminodibenzyl derivatives demonstrated anti-leishmanial activity. Iminodibenzyl, in combination with 3-methyl-2-benzothiazolinonehydrazone hydrochloride are used as chromogenic co-substrates for quantification of hydrogen peroxide and glucose.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
In vitro studies of DNA damage caused by tricyclic antidepressants: a role of peroxidase in the side effects of the drugs.	2010 Sep 20	20804147
Iminodibenzyl class antipsychotics for schizophrenia: a systematic review and meta-analysis of carpipramine, clocapramine, and mosapramine.	2014	25525363
New iminodibenzyl derivatives with anti-leishmanial activity.	2017 Jul	28414928

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:45:08 GMT 2023` Edited by `admin` on `Fri Dec 15 15:45:08 GMT 2023`
Record UNII	262BX7OE3U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IMINODIBENZYL

Common Name

English

10,11-DIHYDRODIBENZ(B,F)AZEPINE

Systematic Name

English

5H-DIBENZ(B,F)AZEPINE, 10,11-DIHYDRO-

Systematic Name

English

CARBAMAZEPINE IMPURITY E [IP]

Common Name

English

10,11-DIHYDRO-5H-DIBENZ(B.F)AZEPINE

Systematic Name

English

IMINODIBENZYL TRIMIPRAMINE [USP IMPURITY]

Common Name

English

10,11-DIHYDRO-5H-DIBENZO(B,F)AZEPINE

Systematic Name

English

CLOMIPRAMINE HYDROCHLORIDE IMPURITY E [EP IMPURITY]

Common Name

English

2,2'-IMINOBIBENZYL

Common Name

English

2,2'-IMINODIBENZYL

Common Name

English

IMINOBIBENZYL

Systematic Name

English

TRIMIPRAMINE MALEATE IMPURITY F [EP IMPURITY]

Common Name

English

CARBAMAZEPINE IMPURITY E [EP IMPURITY]

Common Name

English

NSC-72110

Code

English

Code System Code Type Description

FDA UNII

262BX7OE3U