1,2-DIETHYLBENZENE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H14
Molecular Weight	134.2182
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC1=CC=CC=C1CC

InChI

InChIKey=KVNYFPKFSJIPBJ-UHFFFAOYSA-N

InChI=1S/C10H14/c1-3-9-7-5-6-8-10(9)4-2/h5-8H,3-4H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C10H14
Molecular Weight	134.2182
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Prevalence of ocular, respiratory and cutaneous symptoms in indoor swimming pool workers and exposure to disinfection by-products (DBPs).	2010-04	20617036
Probing mechanisms of axonopathy. Part II: Protein targets of 2,5-hexanedione, the neurotoxic metabolite of the aliphatic solvent n-hexane.	2009-02	19033394
Probing mechanisms of axonopathy. Part I: Protein targets of 1,2-diacetylbenzene, the neurotoxic metabolite of aromatic solvent 1,2-diethylbenzene.	2008-09	18502740
Bio-distribution study of 1,2-diethylbenzene and its main metabolites by whole-body autoradiography and tissue homogenates.	2008-09	18253718
Nanoporous organosilicas as preconcentration materials for the electrochemical detection of trinitrotoluene.	2008-06-15	18470994
Axonopathy-inducing 1,2-diacetylbenzene forms adducts with motor and cytoskeletal proteins required for axonal transport.	2007-12	17577667
Using supercritical fluid chromatography to determine diffusion coefficients of 1,2-diethylbenzene, 1,4-diethylbenzene, 5-tert-butyl-m-xylene and phenylacetylene in supercritical carbon dioxide.	2007-10-12	17850810
Environmental metabolite, 1,2-diacetylbenzene, produces cytotoxicity through ROS generation in HUVEC cells.	2007-08	17654252
A liquid chromatographic-mass spectrometric method to evaluate the distribution kinetics of 1,2-diethylbenzene and its metabolite 1,2-diacetylbenzene in the F344 male rat.	2007-01	17162499
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
A new murine model of giant proximal axonopathy.	2005-04	15759132
Theoretical determination of chromophores in the chromogenic effects of aromatic neurotoxicants.	2002-03-20	11890826
Aromatic as well as aliphatic hydrocarbon solvent axonopathy.	2002-03	12018006
1,2-diacetylbenzene, the neurotoxic metabolite of a chromogenic aromatic solvent, induces proximal axonopathy.	2001-12-01	11740911
Toxicokinetics and metabolism of 1,2-diethylbenzene in male Sprague Dawley rats--part 2: evidence for in vitro and in vivo stereoselectivity of 1,2-diethylbenzene metabolism.	2001-06	11353756

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:40:15 GMT 2025` Edited by `admin` on `Mon Mar 31 19:40:15 GMT 2025`
Record UNII	25HOX6T1LU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,2-DIETHYLBENZENE

Systematic Name

English

1,2-DIETHYLBENZENE [HSDB]

Preferred Name

English

BENZENE, O-DIETHYL-

Common Name

English

BENZENE, 1,2-DIETHYL-

Systematic Name

English

O-DIETHYLBENZENE

Common Name

English

Code System Code Type Description

FDA UNII

25HOX6T1LU