IMPACARZINE

Possibly Marketed Outside US

First approved in 2020

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H55N5O2
Molecular Weight	493.7686
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCN1CCN(CCN2CCN(CC2)C(=O)N(CC)CC)C1=O

InChI

InChIKey=OQXWEZVLEIJVSI-UHFFFAOYSA-N

InChI=1S/C28H55N5O2/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-31-25-26-33(28(31)35)24-21-29-19-22-32(23-20-29)27(34)30(5-2)6-3/h4-26H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C28H55N5O2
Molecular Weight	493.7686
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/525526 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19730412&CC=DE&NR=2150438A1&KC=A1

Impacarzine is cyclic urea derivative patented by pharmaceutical company Asta-Werke A.-G. as antiviral agent. In preclinical models Impacarzine gave 25% protection to mice infected with Influenza A2/Hongkong virus.

Originator

Approval Year

PubMed

Title	Date	PubMed
Influence of a new virostatic compound on the induction of enzymes in rat liver.	1975-09	24

Patents

Sample Use Guides

In Vivo Use Guide

mice: 10 mg/kg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:16:24 GMT 2025` Edited by `admin` on `Mon Mar 31 18:16:24 GMT 2025`
Record UNII	25G65PH99M
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IMPACARZINE

Official Name

English

impacarzine [INN]

Preferred Name

English

N,N-DIETHYL-4-(2-(2-OXO-3-TETRADECYL-1-IMIDAZOLIDINYL)ETHYL)-1-PIPERAZINECARBOXAMIDE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281