Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C38H80N |
| Molecular Weight | 551.0485 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 1 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC
InChI
InChIKey=OGQYPPBGSLZBEG-UHFFFAOYSA-N
InChI=1S/C38H80N/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h5-38H2,1-4H3/q+1
| Molecular Formula | C38H80N |
| Molecular Weight | 551.0485 |
| Charge | 1 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Distearyl dimethyl ammonium bromide (or dimethyldioctadecylammonium bromide (or DDA), a quaternary ammonium salt, that stimulates immune responses and binds to antigens. DDA enhances the immunogenicity of the soluble antigen. It was shown, that complexes of DDA and antigen were effective in eliciting a delayed hypersensitivity reaction, which was desirable for an antitumor effect. Besides, as a part of liposomal adjuvants, DDA can modulate T-helper 1-immune responses.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The enhancement of humoral and cellular immune responses by dimethyldioctadecylammonium bromide. | 1980 Feb |
|
| Interaction of antigens with dimethyldioctadecylammonium bromide, a chemically defined biological response modifier. | 1982 Dec |
|
| Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen. | 2010 Mar 3 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:46:29 UTC 2023
by
admin
on
Fri Dec 15 15:46:29 UTC 2023
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| Record UNII |
251IW5I21C
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| Record Status |
Validated (UNII)
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251IW5I21C
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1311550
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DB14143
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251IW5I21C
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C015831
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14357-21-2
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DTXSID00859191
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7880
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| Related Record | Type | Details | ||
|---|---|---|---|---|
|
IONIC MOIETY |
