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Details

Stereochemistry ACHIRAL
Molecular Formula FHO3P.H4N
Molecular Weight 117.0168
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MONOAMMONIUM MONOFLUOROPHOSPHATE

SMILES

[NH4+].OP([O-])(F)=O

InChI

InChIKey=UZASADVOSTVZTB-UHFFFAOYSA-N
InChI=1S/FH2O3P.H3N/c1-5(2,3)4;/h(H2,2,3,4);1H3

HIDE SMILES / InChI

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula FH2O3P
Molecular Weight 99.9862
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Monofluorophosphate (MFP) is an anion, which is a phosphate group with one oxygen atom substituted with a fluorine atom. Sodium Monofluorophosphate is intended to be used by both petitioners in food supplements as a source of fluoride in the forms of multi-vitamin, multi-mineral supplements, solid tablets or tablets dispersible in liquid. The toxic effects of Monofluorophosphate are attributable to the fluoride ion released by the in vivo hydrolysis of the parent compound. The Monofluorophosphate ion appears to play no role. The acute toxicity of Monofluorophosphate is somewhat less than that of NaF, due to the lesser availability of fluoride in the short term from Monofluorophosphate. In the long term, Monofluorophosphate produces virtually the same picture of renal effects and skeletal storage of fluoride as does NaF. Sodium Monofluorophosphate dissociates into sodium and Monofluorophosphate ions in the intestinal tract, the latter being absorbed mainly in the upper small intestine.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
3.4 mM [Ki]
69.0 µM [Ki]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
AMERFRESH

Approved Use

helps potect against cavities.

Launch Date

1996
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 11:27:02 GMT 2023
Edited
by admin
on Sat Dec 16 11:27:02 GMT 2023
Record UNII
250X2251N1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MONOAMMONIUM MONOFLUOROPHOSPHATE
Systematic Name English
NSC-404121
Code English
PHOSPHOROFLUORIDIC ACID, MONOAMMONIUM SALT
Systematic Name English
Code System Code Type Description
PUBCHEM
18940159
Created by admin on Sat Dec 16 11:27:02 GMT 2023 , Edited by admin on Sat Dec 16 11:27:02 GMT 2023
PRIMARY
EPA CompTox
DTXSID001021845
Created by admin on Sat Dec 16 11:27:02 GMT 2023 , Edited by admin on Sat Dec 16 11:27:02 GMT 2023
PRIMARY
FDA UNII
250X2251N1
Created by admin on Sat Dec 16 11:27:02 GMT 2023 , Edited by admin on Sat Dec 16 11:27:02 GMT 2023
PRIMARY
NSC
404121
Created by admin on Sat Dec 16 11:27:02 GMT 2023 , Edited by admin on Sat Dec 16 11:27:02 GMT 2023
PRIMARY
CAS
66115-19-3
Created by admin on Sat Dec 16 11:27:02 GMT 2023 , Edited by admin on Sat Dec 16 11:27:02 GMT 2023
ALTERNATIVE
CAS
20859-38-5
Created by admin on Sat Dec 16 11:27:02 GMT 2023 , Edited by admin on Sat Dec 16 11:27:02 GMT 2023
PRIMARY