2-MERCAPTOIMIDAZOLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H6N2S
Molecular Weight	102.158
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

S=C1NCCN1

InChI

InChIKey=PDQAZBWRQCGBEV-UHFFFAOYSA-N

InChI=1S/C3H6N2S/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6)

HIDE SMILES / InChI

Molecular Formula	C3H6N2S
Molecular Weight	102.158
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Zebrafish eleutheroembryos provide a suitable vertebrate model for screening chemicals that impair thyroid hormone synthesis.	2011-09-01	21800831
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.	2011-03-28	21251949
Metal mediated C-S rupture of heterocyclic thioamides: in situ generation of 2,2'-thio-di-2-imidazoline, 1,1'-dimethyl-2,2'-di-imidazolylsulfide, SO4(2-) and their variable coordination to Cu(II).	2010-09-14	20676416
Penta-carbon-yl(imidazolidine-2-thione-κS)tungsten(0).	2010-05-08	21579284
Synthesis and biological activity of some new 1-benzyl and 1-benzoyl-3-heterocyclic indole derivatives.	2010-03	20228041
Experimental and computational approach to the rational monitoring of hydrogen-bonding interaction of 2-Imidazolidinethione with DNA and guanine.	2010-01	19766693
N-acylated and N,N'-diacylated imidazolidine-2-thione derivatives and N,N'-diacylated tetrahydropyrimidine-2(1H)-thione analogues: synthesis and antiproliferative activity.	2009-03	18667259
Perchlorate and ethylenethiourea induce different histological and molecular alterations in a non-mammalian vertebrate model of thyroid goitrogenesis.	2009-01-27	18801409
2-Bromo-1,3-diphenyl-propan-1,3-dione.	2008-11-26	21581407
Sono-synthesis of imidazolidine-2-thione as a base compound of some pharmaceutical products.	2008-02	17446113
Complexations of Hg(CN)(2) with imidazolidine-2-thione and its derivatives: solid state, solution NMR and antimicrobial activity studies.	2007-12-31	17485240
The contribution of the sonic hedgehog cascade in the development of the enteric nervous system in fetal rats with anorectal malformations.	2007-12	18082712
(1,3-Dimethylimidazolidine-2-selone-kappaSe)bis(1,10-phenanthroline-kappa2N,N')copper(II) bis(perchlorate) and bis(2,2'-bipyridyl-kappa2N,N')(imidazolidine-2-thione-kappaS)copper(II) bis(perchlorate).	2007-08	17675685
Synthesis and characterization of mixed-metal complexes of Ag/Cu and W/Mo and a complex of Ag with heterocyclic thione ligands.	2007-07-21	17607410
The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties.	2007	18389065
Sonic hedgehog, BMP4, and Hox genes in the development of anorectal malformations in Ethylenethiourea-exposed fetal rats.	2006-12	17161201
Synthesis of 1D {Cu6(mu3-SC3H6N2)4(mu-SC3H6N2)2(mu-I)2I4}n and 3D {Cu2(mu-SC3H6N2)2(mu-SCN)2}n polymers with 1,3-imidazolidine-2-thione: bond isomerism in polymers.	2006-11-13	17083240
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by chemicals carcinogenic to the rat thyroid.	2006-10-30	16942904
Photodegradation kinetics of some thiols and thiones in aqueous suspension of zinc oxide.	2006-07-22	16856757
Expression of sodium-iodide symporter mRNA in the thyroid gland of Xenopus laevis tadpoles: developmental expression, effects of antithyroidal compounds, and regulation by TSH.	2006-07	16837620
Effects of tetrabromobisphenol A on larval development and thyroid hormone-regulated biomarkers of the amphibian Xenopus laevis.	2006-07	16290818
Evaluation of histological and molecular endpoints for enhanced detection of thyroid system disruption in Xenopus laevis tadpoles.	2006-04	16396842
Sonic hedgehog expression in the development of hindgut in ETU-exposed fetal rats.	2006-01	16369776
Syntheses of 1,3-Imidazoline-2-thione and 2-Phenylimino-1,3-thiazoline combinatorial libraries through different sequences of the same components.	2005-11-15	16283792
1,3-Dibenzoylimidazolidine-2-thione and 1,3-dibenzoyl-3,4,5,6-tetrahydropyrimidine-2(1H)-thione.	2005-06	15930680
Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics.	2005-04	15864117
Versatility of heterocyclic thioamides in the construction of a trinuclear cluster [Cu3I3(dppe)3 (SC5H4NH)] and Cu(I) linear polymers {Cu6(SC5H4NH)6I6}n x 2nCH3CN and {Cu(I)6 (SC3H6N2)6X6}n (X = Br, I).	2005-03-21	15762717
Reappraising the formation of Jaffé's Base: studies of the treatment of imidazolidine-2-thione with mild oxidising agents.	2003-09-21	14527154
A simple method for the determination of ethylene-thiourea (ETU) in biological samples.	2002-06-11	12054362
Fluoronucleosides, isothiocyanato C-nucleosides, and thioureylene di-C-nucleosides via cyclic sulfates.	2002-04-19	11950304
Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.	2002-04	11940454
Comparative (13)C and (31)P NMR studies of the ligand exchange reactions of auranofin with ergothionine, imidazolidine-2-thione and diazinane-2-thione.	2002-01-01	11750025
Synthesis of beta-D-galactofuranosyl nucleoside analogues. A new type of beta-D-galactofuranosidase inhibitor.	2001-07-03	11448672
Thyroid peroxidase as toxicity target for dithiocarbamates.	1997	9248629
Cloning of a new FRTL5-derived cell line stably expressing active human thyroid peroxidase.	1995-07-17	7626075
Endometrial carcinogenesis induced by concurrent oral administration of ethylenethiourea and sodium nitrite in mice.	1994-10	7955072
Dithiocarbamate fungicides decrease histochemical reactivity of cholinesterases in the gut wall of the rat.	1985	3868355
Allergic contact dermatitis from ethylene thiourea.	1983-05	6861483

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:48:53 GMT 2025` Edited by `admin` on `Mon Mar 31 20:48:53 GMT 2025`
Record UNII	24FOJ4N18S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETHYLENE THIOUREA

Preferred Name

English

2-MERCAPTOIMIDAZOLINE

Systematic Name

English

2-IMIDAZOLIDIMETHIONE

Common Name

English

1,3-ETHYLENE-2-THIOUREA

Common Name

English

ETHYLENETHIOUREA [IARC]

Common Name

English

SOXINOL 22

Brand Name

English

1H-IMIDAZOLE-2-THIOL, 4,5-DIHYDRO-

Systematic Name

English

IMIDAZOLIDINE-2-THIONE

Systematic Name

English

ETHYLENE THIOUREA [HSDB]

Common Name

English

2-IMIDAZOLIDINETHIONE

Systematic Name

English

2-THIOL-DIHYDROGLYOXALINE

Common Name

English

ETHYLENE THIOUREA [MI]

Common Name

English

MERCOZEN

Brand Name

English

2-MERCAPTO-4,5-DIHYDROIMIDAZOLE

Systematic Name

English

ETHYLENETHIOUREA

Common Name

English

SANCELLER 22

Brand Name

English

2-MERCAPTO-2-IMIDAZOLINE

Systematic Name

English

ROBAC 22

Brand Name

English

2-IMIDAZOLINE-2-THIOL

Systematic Name

English

Classification Tree Code System Code

CFR

21 CFR 189.250