2-MERCAPTOIMIDAZOLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H6N2S
Molecular Weight	102.158
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

S=C1NCCN1

InChI

InChIKey=PDQAZBWRQCGBEV-UHFFFAOYSA-N

InChI=1S/C3H6N2S/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6)

HIDE SMILES / InChI

Molecular Formula	C3H6N2S
Molecular Weight	102.158
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Allergic contact dermatitis from ethylene thiourea.	1983 May	6861483
Dithiocarbamate fungicides decrease histochemical reactivity of cholinesterases in the gut wall of the rat.	1985	3868355
Endometrial carcinogenesis induced by concurrent oral administration of ethylenethiourea and sodium nitrite in mice.	1994 Oct	7955072
Cloning of a new FRTL5-derived cell line stably expressing active human thyroid peroxidase.	1995 Jul 17	7626075
Thyroid peroxidase as toxicity target for dithiocarbamates.	1997	9248629
Synthesis of beta-D-galactofuranosyl nucleoside analogues. A new type of beta-D-galactofuranosidase inhibitor.	2001 Jul 3	11448672
Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.	2002 Apr	11940454
Fluoronucleosides, isothiocyanato C-nucleosides, and thioureylene di-C-nucleosides via cyclic sulfates.	2002 Apr 19	11950304
Comparative (13)C and (31)P NMR studies of the ligand exchange reactions of auranofin with ergothionine, imidazolidine-2-thione and diazinane-2-thione.	2002 Jan 1	11750025
A simple method for the determination of ethylene-thiourea (ETU) in biological samples.	2002 May-Jun	12054362
Reappraising the formation of Jaffé's Base: studies of the treatment of imidazolidine-2-thione with mild oxidising agents.	2003 Sep 21	14527154
Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics.	2005 Apr	15864117
1,3-Dibenzoylimidazolidine-2-thione and 1,3-dibenzoyl-3,4,5,6-tetrahydropyrimidine-2(1H)-thione.	2005 Jun	15930680
Versatility of heterocyclic thioamides in the construction of a trinuclear cluster [Cu3I3(dppe)3 (SC5H4NH)] and Cu(I) linear polymers {Cu6(SC5H4NH)6I6}n x 2nCH3CN and {Cu(I)6 (SC3H6N2)6X6}n (X = Br, I).	2005 Mar 21	15762717
Syntheses of 1,3-Imidazoline-2-thione and 2-Phenylimino-1,3-thiazoline combinatorial libraries through different sequences of the same components.	2005 Nov-Dec	16283792
Evaluation of histological and molecular endpoints for enhanced detection of thyroid system disruption in Xenopus laevis tadpoles.	2006 Apr	16396842
Sonic hedgehog, BMP4, and Hox genes in the development of anorectal malformations in Ethylenethiourea-exposed fetal rats.	2006 Dec	17161201
Sonic hedgehog expression in the development of hindgut in ETU-exposed fetal rats.	2006 Jan	16369776
Expression of sodium-iodide symporter mRNA in the thyroid gland of Xenopus laevis tadpoles: developmental expression, effects of antithyroidal compounds, and regulation by TSH.	2006 Jul	16837620
Effects of tetrabromobisphenol A on larval development and thyroid hormone-regulated biomarkers of the amphibian Xenopus laevis.	2006 Jul	16290818
Photodegradation kinetics of some thiols and thiones in aqueous suspension of zinc oxide.	2006 May-Jun	16856757
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Synthesis of 1D {Cu6(mu3-SC3H6N2)4(mu-SC3H6N2)2(mu-I)2I4}n and 3D {Cu2(mu-SC3H6N2)2(mu-SCN)2}n polymers with 1,3-imidazolidine-2-thione: bond isomerism in polymers.	2006 Nov 13	17083240
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by chemicals carcinogenic to the rat thyroid.	2006 Oct 30	16942904
The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties.	2007	18389065
(1,3-Dimethylimidazolidine-2-selone-kappaSe)bis(1,10-phenanthroline-kappa2N,N')copper(II) bis(perchlorate) and bis(2,2'-bipyridyl-kappa2N,N')(imidazolidine-2-thione-kappaS)copper(II) bis(perchlorate).	2007 Aug	17675685
The contribution of the sonic hedgehog cascade in the development of the enteric nervous system in fetal rats with anorectal malformations.	2007 Dec	18082712
Complexations of Hg(CN)(2) with imidazolidine-2-thione and its derivatives: solid state, solution NMR and antimicrobial activity studies.	2007 Dec 31	17485240
Synthesis and characterization of mixed-metal complexes of Ag/Cu and W/Mo and a complex of Ag with heterocyclic thione ligands.	2007 Jul 21	17607410
Sono-synthesis of imidazolidine-2-thione as a base compound of some pharmaceutical products.	2008 Feb	17446113
2-Bromo-1,3-diphenyl-propan-1,3-dione.	2008 Nov 26	21581407
Perchlorate and ethylenethiourea induce different histological and molecular alterations in a non-mammalian vertebrate model of thyroid goitrogenesis.	2009 Jan 27	18801409
N-acylated and N,N'-diacylated imidazolidine-2-thione derivatives and N,N'-diacylated tetrahydropyrimidine-2(1H)-thione analogues: synthesis and antiproliferative activity.	2009 Mar	18667259
Experimental and computational approach to the rational monitoring of hydrogen-bonding interaction of 2-Imidazolidinethione with DNA and guanine.	2010 Jan	19766693
Synthesis and biological activity of some new 1-benzyl and 1-benzoyl-3-heterocyclic indole derivatives.	2010 Mar	20228041
Penta-carbon-yl(imidazolidine-2-thione-κS)tungsten(0).	2010 May 8	21579284
Metal mediated C-S rupture of heterocyclic thioamides: in situ generation of 2,2'-thio-di-2-imidazoline, 1,1'-dimethyl-2,2'-di-imidazolylsulfide, SO4(2-) and their variable coordination to Cu(II).	2010 Sep 14	20676416
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.	2011 Mar 28	21251949
Zebrafish eleutheroembryos provide a suitable vertebrate model for screening chemicals that impair thyroid hormone synthesis.	2011 Sep 1	21800831

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:22:31 GMT 2023` Edited by `admin` on `Sat Dec 16 01:22:31 GMT 2023`
Record UNII	24FOJ4N18S
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

2-MERCAPTOIMIDAZOLINE

Systematic Name

English

2-IMIDAZOLIDIMETHIONE

Common Name

English

1,3-ETHYLENE-2-THIOUREA

Common Name

English

ETHYLENETHIOUREA [IARC]

Common Name

English

SOXINOL 22

Brand Name

English

1H-IMIDAZOLE-2-THIOL, 4,5-DIHYDRO-

Systematic Name

English

IMIDAZOLIDINE-2-THIONE

Systematic Name

English

ETHYLENE THIOUREA [HSDB]

Common Name

English

2-IMIDAZOLIDINETHIONE

Systematic Name

English

ETHYLENE THIOUREA

Systematic Name

English

2-THIOL-DIHYDROGLYOXALINE

Common Name

English

ETHYLENE THIOUREA [MI]

Common Name

English

MERCOZEN

Brand Name

English

2-MERCAPTO-4,5-DIHYDROIMIDAZOLE

Systematic Name

English

ETHYLENETHIOUREA

Common Name

English

SANCELLER 22

Brand Name

English

2-MERCAPTO-2-IMIDAZOLINE

Systematic Name

English

ROBAC 22

Brand Name

English

2-IMIDAZOLINE-2-THIOL

Systematic Name

English

Classification Tree Code System Code

CFR

21 CFR 189.250