CLOGUANAMIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H8ClN5O
Molecular Weight	237.646
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CLOGUANAMIL

Structure Search

SMILES

NC(=N)NC(=O)NC1=CC(Cl)=C(C=C1)C#N

InChI

InChIKey=FEYBPSKVORXMON-UHFFFAOYSA-N

InChI=1S/C9H8ClN5O/c10-7-3-6(2-1-5(7)4-11)14-9(16)15-8(12)13/h1-3H,(H5,12,13,14,15,16)

HIDE SMILES / InChI

Molecular Formula	C9H8ClN5O
Molecular Weight	237.646
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4788209 | https://books.google.ru/books?id=ngLUHsfpbJUC&pg=PA277&lpg=PA277

Cloguanamil is an antiprotozoal agent, useful against malaria parasites. The drug was synthesized by Wellcome Research Laboratories in the 1970s.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Predictions of the antimalarial activity of arylamidinoureas.	1973-08	4788209

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:53:05 GMT 2025` Edited by `admin` on `Mon Mar 31 17:53:05 GMT 2025`
Record UNII	24484LU3FJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

57C65

Preferred Name

English

CLOGUANAMIL

Official Name

English

cloguanamil [INN]

Common Name

English

1-AMIDINO-3-(3-CHLORO-4-CYANOPHENYL) UREA

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

Code System Code Type Description

SMS_ID

100000084319

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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FDA UNII

24484LU3FJ

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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PUBCHEM

30760

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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CAS

21702-93-2

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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NCI_THESAURUS

C80847

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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MESH

C010089

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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ChEMBL

CHEMBL1697687

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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EPA CompTox

DTXSID40176091

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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EVMPD

SUB06715MIG

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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INN

3221

Created by admin on Mon Mar 31 17:53:05 GMT 2025 , Edited by admin on Mon Mar 31 17:53:05 GMT 2025

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					24484LU3FJ

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