Vecantoxatug

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 21:29:02 GMT 2025` Edited by `admin` on `Wed Apr 02 21:29:02 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	23XK2FKX5P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Vecantoxatug

Official Name

English

H-gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-69*02 (81.4%) -(IGHD) -IGHJ4*01 (85.7%) L123>M (110), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115) -Homo sapiens IGHG1*03 (100%) G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (212) (116-213)

Preferred Name

English

immunoglobulin G1-kappa, anti-[Clostridium tetani tetanus toxin (TeNT, neurotoxin)], humanized monoclonal antibody (vecantoxatug)

Common Name

English

Immunoglobulin G1, anti-(Clostridium tetani tetanus toxin) (human-Mus musculus monoclonal GR2001 ?1-chain), disulfide with human-Mus musculus monoclonal GR2001 ?-chain, dimer

Common Name

English

vecantoxatug [INN]

Common Name

English

Code System Code Type Description

FDA UNII

23XK2FKX5P

Created by admin on Wed Apr 02 21:29:02 GMT 2025 , Edited by admin on Wed Apr 02 21:29:02 GMT 2025

PRIMARY

INN

13380

Created by admin on Wed Apr 02 21:29:02 GMT 2025 , Edited by admin on Wed Apr 02 21:29:02 GMT 2025

PRIMARY

CAS

2956766-52-0

Created by admin on Wed Apr 02 21:29:02 GMT 2025 , Edited by admin on Wed Apr 02 21:29:02 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_142	2_198
2_218	4_214
2_259	2_319
1_142	1_198
2_365	2_423
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_218	3_214
1_224	2_224
1_227	2_227
1_259	1_319
1_365	1_423

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_295
N	2_295

Related Record Type Details


					23XK2FKX5P

Vecantoxatug

ACTIVE MOIETY

Comments:

anti-[Clostridium tetani tetanus toxin

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_445] [2_445]	C-TERMINUS	K		LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	Q		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL