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Details

Stereochemistry ACHIRAL
Molecular Formula C24H23NO2
Molecular Weight 357.4449
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 5-OH-JWH-018

SMILES

OCCCCCN1C=C(C(=O)C2=CC=CC3=C2C=CC=C3)C4=CC=CC=C14

InChI

InChIKey=UGHBAICDASCCIQ-UHFFFAOYSA-N
InChI=1S/C24H23NO2/c26-16-7-1-6-15-25-17-22(20-12-4-5-14-23(20)25)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17,26H,1,6-7,15-16H2

HIDE SMILES / InChI
Molecular Formula C24H23NO2
Molecular Weight 357.4449
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

5-OH-JWH-018 is a major urinary metabolite of JWH 018, a mildly selective agonist of the peripheral cannabinoid (CB2) receptor. 5-OH-JWH-018 is characterized by monohydroxylation of the N-alkyl chain, which is almost completely glucuronidated in urine samples.

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
UDP-glucuronosyltransferase
2
Target ID: UDP-glucuronosyltransferase
Substrate
661
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Detection of JWH-018 metabolites in smoking mixture post-administration urine.
2010 Jul 15

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 18:10:32 GMT 2023
Edited
by admin
on Sat Dec 16 18:10:32 GMT 2023
Record UNII
23VQ914XMN
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
5-OH-JWH-018
Common Name English
J2.967.081A
Code English
JWH-018 N-5-OH M
Common Name English
JWH-018 N-(5-HYDROXYPENTYL)
Common Name English
1-(5-HYDROXYPENTYL)-3-(1-NAPHTHYLCARBONYL)-1H-INDOLE
Systematic Name English
METHANONE, (1-(5-HYDROXYPENTYL)-1H-INDOL-3-YL)-1-NAPHTHALENYL-
Systematic Name English
Code System Code Type Description
FDA UNII
23VQ914XMN
Created by admin on Sat Dec 16 18:10:33 GMT 2023 , Edited by admin on Sat Dec 16 18:10:33 GMT 2023
PRIMARY
EPA CompTox
DTXSID401016539
Created by admin on Sat Dec 16 18:10:33 GMT 2023 , Edited by admin on Sat Dec 16 18:10:33 GMT 2023
PRIMARY
PUBCHEM
53394450
Created by admin on Sat Dec 16 18:10:33 GMT 2023 , Edited by admin on Sat Dec 16 18:10:33 GMT 2023
PRIMARY
CAS
335161-21-2
Created by admin on Sat Dec 16 18:10:33 GMT 2023 , Edited by admin on Sat Dec 16 18:10:33 GMT 2023
PRIMARY
NIH
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