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VELAGLUCERASE ALFA
23HYE36B0I
US Approved Rx (2010)
First approved in 2010
General
Record Details
Names
16
Classification
7
Identifiers
16
Subunits
1
Disulfide Links
2
Glycosylation
4
Active Moiety
1
Characteristic Attributes
2
VELAGLUCERASE ALFA
23HYE36B0I
US Approved Rx (2010)
First approved in 2010
General
Approval Year
2010
465
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
23HYE36B0I
Record Status
Validated (UNII)
Record Version
22
21
20
19
18
17
16
15
14
13
12
11
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8
7
6
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4
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2
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Names
16
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entries
Name
Type
Language
Name
Type
Language
VELAGLUCERASE ALFA
Official Name
English
velaglucerase alfa [INN]
Common Name
English
VELAGLUCERASE ALFA [JAN]
Common Name
English
VELAGLUCERASE ALFA [EMA EPAR]
Common Name
English
EC-3.2.1.45
Code
English
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4
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Classification
7
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Positive
EU ORPHAN DRUG
Positive
Treatment of Gaucher disease
EU-Orphan Drug
EU/3/10/752
Enzymes
ATC
ALIMENTARY TRACT AND METABOLISM
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Enzymes
velaglucerase alfa
WHO-ATC
A16AB10
Biological Agent
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Enzyme Replacement or Supplement Agent
NCI_THESAURUS
C29726
SPHINGOLIPIDOSES
EMA EPAR
DISEASES
NERVOUS SYSTEM DISEASES
CENTRAL NERVOUS SYSTEM DISEASES
BRAIN DISEASES
BRAIN DISEASES, METABOLIC
BRAIN DISEASES, METABOLIC, INBORN
LYSOSOMAL STORAGE DISEASES, NERVOUS SYSTEM
SPHINGOLIPIDOSES
GAUCHER DISEASE
EMA ASSESSMENT REPORTS
VPRIV (AUTHORIZED: GAUCHER DISEASE)
Enzymes
VATC
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Enzymes
velaglucerase alfa
WHO-VATC
QA16AB10
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Identifiers
16
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Code System
Code
Type
Description
Code System
Code
Type
Description
INN
8925
PRIMARY
WIKIPEDIA
VELAGLUCERASE ALFA
PRIMARY
NCI_THESAURUS
C87735
PRIMARY
CAS
884604-91-5
PRIMARY
DRUG BANK
DB06720
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Disulfide Links
2
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entries
From
To
From
To
1_4
1_16
1_18
1_23
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Glycosylation
4
Glycosylation Type
HUMAN
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Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_19
N
1_146
N
1_270
N
1_462
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Active Moiety
1
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entries
Related Record
Type
Details
Related Record
Type
Details
23HYE36B0I
VELAGLUCERASE ALFA
ACTIVE MOIETY
Amount:
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Molecular Formula
CHEMICAL
ESTIMATED
C2532H3835N672O711S16
MOL_WEIGHT:APPROXIMATE
CHEMICAL
APPROXIMATE 55597.1 Da (average)
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