U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 21:59:40 GMT 2025
Edited
by admin
on Mon Mar 31 21:59:40 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
237GB6IDKO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TIGATUZUMAB
INN   WHO-DD  
INN  
Official Name English
tigatuzumab [INN]
Preferred Name English
ANTI-TRAIL-R2 MOAB
Common Name English
Tigatuzumab [WHO-DD]
Common Name English
CS-1008
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CYTOKINE RECEPTOR DR5 (DEATH RECEPTOR 5)) (HUMAN-MOUSE MONOCLONAL TRA-8 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL TRA-8 .KAPPA.-CHAIN, DIMER
Systematic Name English
ANTI-DR5 MOAB
Common Name English
TRA-8
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
Code System Code Type Description
INN
8979
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
FDA UNII
237GB6IDKO
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
WIKIPEDIA
TIGATUZUMAB
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
DRUG BANK
DB15101
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
NCI_THESAURUS
C62482
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
EVMPD
SUB124908
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
ChEMBL
CHEMBL1743080
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
SMS_ID
100000146036
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
CAS
918127-53-4
Created by admin on Mon Mar 31 21:59:40 GMT 2025 , Edited by admin on Mon Mar 31 21:59:40 GMT 2025
PRIMARY
From To
1_22 1_96
1_146 1_202
1_222 3_213
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
2_22 2_96
2_146 2_202
2_222 4_213
2_263 2_323
2_369 2_427
3_23 3_88
3_133 3_193
4_23 4_88
4_133 4_193
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B
TARGET -> INHIBITOR
Related Record Type Details
TIGATUZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:ESTIMATE CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966