1,4-Bis(3-aminopropyl)piperazine adipate (1:1)

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H24N4.C6H10O4
Molecular Weight	346.4656
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 1,4-Bis(3-aminopropyl)piperazine adipate (1:1)

Structure Search

SMILES

OC(=O)CCCCC(O)=O.NCCCN1CCN(CCCN)CC1

InChI

InChIKey=ZWPKWMGPJWNIKP-UHFFFAOYSA-N

InChI=1S/C10H24N4.C6H10O4/c11-3-1-5-13-7-9-14(10-8-13)6-2-4-12;7-5(8)3-1-2-4-6(9)10/h1-12H2;1-4H2,(H,7,8)(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C10H24N4
Molecular Weight	200.3244
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H10O4
Molecular Weight	146.1412
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Recent news related to substrates and inhibitors of plant amine oxidases.	2003 Apr 11	12686157
Synthesis and in vitro and in vivo antimalarial activity of N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine derivatives.	2003 Feb 13	12570376
Synthesis and antimalarial evaluation of new 1,4-bis(3-aminopropyl)piperazine derivatives.	2003 Nov 3	14552779
Synthesis, antimalarial activity, and molecular modeling of new pyrrolo[1,2-a]quinoxalines, bispyrrolo[1,2-a]quinoxalines, bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and bispyrrolo[1,2-a]thieno[3,2-e]pyrazines.	2004 Apr 8	15055999
1,4-bis(3-aminopropyl)piperazine libraries: from the discovery of classical chloroquine-like antimalarials to the identification of new targets.	2005 Feb	15720196
[Thieno[3,2-c]quinoline-4-yl-amines--synthesis and investigation of activity against malaria].	2006 Apr	16649537
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.	2007 Jul 1	17493808
One pot synthesis of pyrimidine and bispyrimidine derivatives and their evaluation for anti-inflammatory and analgesic activities.	2007 May 15	17383186
Designed pendant chain covalently bonded to silica gel for cation removal.	2008 Aug 15	18191024
Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents.	2008 Jan 15	17967541
Synthesis, structure, and polymorphism studies in amine-templated open-framework zinc phosphites.	2008 Jun 16	18459767
Synthesis and preliminary evaluation of new ursolic and oleanolic acids derivatives as antileishmanial agents.	2008 Oct	18608757
New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity.	2008 Oct 15	18819813
Synthesis, characterization, and properties of organically templated lanthanide oxalatophosphates with a three-dimensional honeycomb structure: (H4APPIP)[Ln3(C2O4)(5.5)(H2PO4)2].5H2O (Ln = Er-Lu, APPIP = 1,4-bis(3-aminopropyl)piperazine).	2009 Feb 16	19159316
Layer silicates modified with 1,4-bis(3-aminopropyl)piperazine for the removal of Th(IV), U(VI) and Eu(III) from aqueous media.	2009 Nov 15	19604631
Designed pendant chain covalently bonded to analogue of heulandite for removal of divalent toxic metals from aqueous solution: thermodynamic and equilibrium study.	2009 Sep 1	19524249
Synthesis and in vitro biological evaluation of new polyamine conjugates as potential anticancer drugs.	2010 Dec	20974504
Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine.	2010 Jul 15	20538470

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 12:01:35 GMT 2023` Edited by `admin` on `Sat Dec 16 12:01:35 GMT 2023`
Record UNII	235PYP9YSL
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

1,4-Bis(3-aminopropyl)piperazine adipate (1:1)

Systematic Name

English

Adipic acid, compd. with 1,4-bis(3-aminopropyl)piperazine (1:1)

Systematic Name

English

Hexanedioic acid, compd. with 1,4-piperazinedipropanamine (1:1)

Systematic Name

English

NSC-13218

Code

English

Adipic acid, compound with 1,4-bis(3-aminopropyl)piperazine (1:1)

Systematic Name

English

Piperazine, 1,4-bis(3-aminopropyl)-, adipate (1:1)

Systematic Name

English

1,4-Piperazinedipropanamine, hexanedioate (1:1)

Systematic Name

English

Code System Code Type Description

CAS

5423-61-0