1,4-Bis(3-aminopropyl)piperazine adipate (1:1)

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H24N4.C6H10O4
Molecular Weight	346.4656
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 1,4-Bis(3-aminopropyl)piperazine adipate (1:1)

Structure Search

SMILES

OC(=O)CCCCC(O)=O.NCCCN1CCN(CCCN)CC1

InChI

InChIKey=ZWPKWMGPJWNIKP-UHFFFAOYSA-N

InChI=1S/C10H24N4.C6H10O4/c11-3-1-5-13-7-9-14(10-8-13)6-2-4-12;7-5(8)3-1-2-4-6(9)10/h1-12H2;1-4H2,(H,7,8)(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C6H10O4
Molecular Weight	146.1412
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C10H24N4
Molecular Weight	200.3244
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Synthesis and in vitro biological evaluation of new polyamine conjugates as potential anticancer drugs.	2010-12	20974504
Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine.	2010-07-15	20538470
Layer silicates modified with 1,4-bis(3-aminopropyl)piperazine for the removal of Th(IV), U(VI) and Eu(III) from aqueous media.	2009-11-15	19604631
Designed pendant chain covalently bonded to analogue of heulandite for removal of divalent toxic metals from aqueous solution: thermodynamic and equilibrium study.	2009-09-01	19524249
Synthesis, characterization, and properties of organically templated lanthanide oxalatophosphates with a three-dimensional honeycomb structure: (H4APPIP)[Ln3(C2O4)(5.5)(H2PO4)2].5H2O (Ln = Er-Lu, APPIP = 1,4-bis(3-aminopropyl)piperazine).	2009-02-16	19159316
New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity.	2008-10-15	18819813
Synthesis and preliminary evaluation of new ursolic and oleanolic acids derivatives as antileishmanial agents.	2008-10	18608757
Designed pendant chain covalently bonded to silica gel for cation removal.	2008-08-15	18191024
Synthesis, structure, and polymorphism studies in amine-templated open-framework zinc phosphites.	2008-06-16	18459767
Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents.	2008-01-15	17967541
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.	2007-07-01	17493808
One pot synthesis of pyrimidine and bispyrimidine derivatives and their evaluation for anti-inflammatory and analgesic activities.	2007-05-15	17383186
[Thieno[3,2-c]quinoline-4-yl-amines--synthesis and investigation of activity against malaria].	2006-04	16649537
1,4-bis(3-aminopropyl)piperazine libraries: from the discovery of classical chloroquine-like antimalarials to the identification of new targets.	2005-02	15720196
Synthesis, antimalarial activity, and molecular modeling of new pyrrolo[1,2-a]quinoxalines, bispyrrolo[1,2-a]quinoxalines, bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and bispyrrolo[1,2-a]thieno[3,2-e]pyrazines.	2004-04-08	15055999
Synthesis and antimalarial evaluation of new 1,4-bis(3-aminopropyl)piperazine derivatives.	2003-11-03	14552779
Recent news related to substrates and inhibitors of plant amine oxidases.	2003-04-11	12686157
Synthesis and in vitro and in vivo antimalarial activity of N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine derivatives.	2003-02-13	12570376

Patents

Substance Class	Chemical Created by `admin` on `Tue Apr 01 17:48:15 GMT 2025` Edited by `admin` on `Tue Apr 01 17:48:15 GMT 2025`
Record UNII	235PYP9YSL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-13218

Preferred Name

English

1,4-Bis(3-aminopropyl)piperazine adipate (1:1)

Systematic Name

English

Adipic acid, compd. with 1,4-bis(3-aminopropyl)piperazine (1:1)

Systematic Name

English

Hexanedioic acid, compd. with 1,4-piperazinedipropanamine (1:1)

Systematic Name

English

Adipic acid, compound with 1,4-bis(3-aminopropyl)piperazine (1:1)

Systematic Name

English

Piperazine, 1,4-bis(3-aminopropyl)-, adipate (1:1)

Systematic Name

English

1,4-Piperazinedipropanamine, hexanedioate (1:1)

Systematic Name

English

Code System Code Type Description

CAS

5423-61-0