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Details

Stereochemistry ACHIRAL
Molecular Formula C24H31N3OS.2C4H4O4
Molecular Weight 641.732
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of BUTAPERAZINE MALEATE

SMILES

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCCC(=O)C1=CC=C2SC3=CC=CC=C3N(CCCN4CCN(C)CC4)C2=C1

InChI

InChIKey=WVYWSPZQGQMPKW-SPIKMXEPSA-N
InChI=1S/C24H31N3OS.2C4H4O4/c1-3-7-22(28)19-10-11-24-21(18-19)27(20-8-4-5-9-23(20)29-24)13-6-12-26-16-14-25(2)15-17-26;2*5-3(6)1-2-4(7)8/h4-5,8-11,18H,3,6-7,12-17H2,1-2H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

HIDE SMILES / InChI

Molecular Formula C4H4O4
Molecular Weight 116.0722
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Molecular Formula C24H31N3OS
Molecular Weight 409.587
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Butaperazine is an antipsychotic phenothiazine. As shown in animal studies butaperazine increases striatal and mesolimbic dopamine turnover. Butaperazine is effective in the management of schizophrenia. Extrapyramidal symptoms and drowsiness are the most common adverse effects.

CNS Activity

Originator

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Spectrophotometric determination of vanadium(V) in minerals, steels, soil and biological samples using phenothiazine derivatives.
2001 Aug
Substance Class Chemical
Created
by admin
on Tue Oct 22 05:57:33 UTC 2019
Edited
by admin
on Tue Oct 22 05:57:33 UTC 2019
Record UNII
22VUW43J2H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BUTAPERAZINE MALEATE
MART.   USAN   WHO-DD  
USAN  
Official Name English
BUTAPERAZINE DIMALEATE
MI  
Common Name English
BUTAPERAZINE MALEATE [USAN]
Common Name English
BUTAPERAZINE MALEATE [WHO-DD]
Common Name English
1-BUTANONE, 1-(10-(3-(4-METHYL-1-PIPERAZINYL)PROPYL)-10H-PHENOTHIAZIN-2-YL)-, (Z)-2-BUTENEDIOATE (1:2)
Systematic Name English
BUTAPERAZINE DIMALEATE [MI]
Common Name English
BUTAPERAZINE MALEATE [MART.]
Common Name English
1-(10-(3-(4-METHYL-1-PIPERAZINYL)PROPYL)PHENOTHIAZIN-2-YL)-1-BUTANONE MALEATE (1:2)
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C66884
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
NCI_THESAURUS C29710
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
Code System Code Type Description
MERCK INDEX
M2789
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
PRIMARY Merck Index
PUBCHEM
6433234
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
PRIMARY
ChEMBL
CHEMBL1697826
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
PRIMARY
ECHA (EC/EINECS)
213-900-5
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
PRIMARY
NCI_THESAURUS
C76440
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
PRIMARY
CAS
1063-55-4
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
PRIMARY
EVMPD
SUB00913MIG
Created by admin on Tue Oct 22 05:57:33 UTC 2019 , Edited by admin on Tue Oct 22 05:57:33 UTC 2019
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY