RHAPONTIGENIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H14O4
Molecular Weight	258.2693
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(O)C=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1

InChI

InChIKey=PHMHDRYYFAYWEG-NSCUHMNNSA-N

InChI=1S/C15H14O4/c1-19-15-5-4-10(8-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+

HIDE SMILES / InChI

Molecular Formula	C15H14O4
Molecular Weight	258.2693
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Potency
Cytochrome P450 1A1 31 Target ID: P04798 Gene ID: 1543.0 Gene Symbol: CYP1A1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/11259321 \| https://www.ncbi.nlm.nih.gov/pubmed/30666906	Inhibitor 8297	0.4 µM [IC50]
Hypoxia-inducible factor 1-alpha 10 Target ID: Q16665 Gene ID: 3091.0 Gene Symbol: HIF1A Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/21628883	Inhibitor 8297
Rac protein signal transduction 1 Target ID: GO:0016601 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24828286	Inhibitor 8297

PubMed

Title	Date	PubMed
Metabolism of Rhaponticin and Activities of its Metabolite, Rhapontigenin: A Review.	2020	30666906

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:24:24 GMT 2023` Edited by `admin` on `Sat Dec 16 18:24:24 GMT 2023`
Record UNII	22BG4NNH6W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RHAPONTIGENIN

Common Name

English

PROTIGENIN

Common Name

English

5-((1E)-2-(3-HYDROXY-4-METHOXYPHENYL)ETHENYL)-1,3-BENZENEDIOL

Systematic Name

English

1,3-BENZENEDIOL, 5-(2-(3-HYDROXY-4-METHOXYPHENYL)ETHENYL)-, (E)-

Systematic Name

English

RHAPONTIN GENIN

Common Name

English

PONTIGENIN

Common Name

English

5-((E)-2-(3-HYDROXY-4-METHOXYPHENYL)ETHENYL)BENZENE-1,3-DIOL

Systematic Name

English

PRONTIGENIN

Common Name

English

RHAPONTIN AGLYCONE

Common Name

English

1,3-BENZENEDIOL, 5-((1E)-2-(3-HYDROXY-4-METHOXYPHENYL)ETHENYL)-

Systematic Name

English

3,3,5-STILBENETRIOL, 4-METHOXY-, (E)-

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

Rhapontigenin