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Details

Stereochemistry ACHIRAL
Molecular Formula C10H18ClN3O2
Molecular Weight 247.722
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SEMUSTINE, CIS-

SMILES

C[C@H]1CC[C@H](CC1)NC(=O)N(CCCl)N=O

InChI

InChIKey=FVLVBPDQNARYJU-DTORHVGOSA-N
InChI=1S/C10H18ClN3O2/c1-8-2-4-9(5-3-8)12-10(15)14(13-16)7-6-11/h8-9H,2-7H2,1H3,(H,12,15)/t8-,9+

HIDE SMILES / InChI

Molecular Formula C10H18ClN3O2
Molecular Weight 247.722
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias.
2000 May
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (MeCCNU).
2002
Interstitial chemotherapy with biodegradable BCNU (Gliadel) wafers in the treatment of malignant gliomas.
2007 Oct
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
2011 Jul 14
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:45:30 GMT 2023
Edited
by admin
on Fri Dec 15 18:45:30 GMT 2023
Record UNII
2281H4FBL9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SEMUSTINE, CIS-
Common Name English
UREA, N-(2-CHLOROETHYL)-N'-(4-METHYLCYCLOHEXYL)-N-NITROSO-, CIS-
Common Name English
1-(2-CHLOROETHYL)-3-(4-METHYLCYCLOHEXYL)-1-NITROSOUREA,, CIS-
Common Name English
NSC-135091
Code English
Code System Code Type Description
FDA UNII
2281H4FBL9
Created by admin on Fri Dec 15 18:45:30 GMT 2023 , Edited by admin on Fri Dec 15 18:45:30 GMT 2023
PRIMARY
CAS
33185-87-4
Created by admin on Fri Dec 15 18:45:30 GMT 2023 , Edited by admin on Fri Dec 15 18:45:30 GMT 2023
PRIMARY
NSC
135091
Created by admin on Fri Dec 15 18:45:30 GMT 2023 , Edited by admin on Fri Dec 15 18:45:30 GMT 2023
PRIMARY