U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 18:11:29 UTC 2021
Edited
by admin
on Sat Jun 26 18:11:29 UTC 2021
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
21Z359Z1CV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CINREBAFUSP ALFA
USAN   INN  
Official Name English
PRS-343
Preferred Name English
IMMUNOGLOBULIN G4 (228-PROLINE, 234-ALANINE, 235-ALANINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR HER2) (HUMAN-MUS MUSCULUS MONOCLONAL PRS-343 .GAMMA.4-CHAIN) FUSION PROTEIN PEPTIDE (SYNTHETIC 15-AMINO ACID LINKER) FUSION PROTEIN WITH LIPOCALIN 2 (HUMAN MU
Common Name English
FUS: MAB HUMANIZED (IGG4) S228P, F234A, L235A ANTI P04626 (ERBB2_HUMAN)RPROT P80188 (NGAL_HUMAN) ANTI Q07011 (TNR9_HUMAN) (PRS343)
Common Name English
(S228>P,F234>A,L235>A) IMMUNOGLOBULIN G4-KAPPA (CHIMERIC HUMAN-MUS MUSCULUS, ANTI-(RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2, ERBB2, HER2)) FUSED ON BOTH HEAVY CHAINS (1-447, 1''-447'') VIA A (G4S)3 LINKER (448-462, 448''-462'') TO A CD137 (TUMOR NECROSIS
Common Name English
CINREBAFUSP ALFA [INN]
Common Name English
CINREBAFUSP ALFA [USAN]
Common Name English
PRS 343 [WHO-DD]
Common Name English
Code System Code Type Description
NCI_THESAURUS
C142890
Created by admin on Sat Jun 26 18:11:29 UTC 2021 , Edited by admin on Sat Jun 26 18:11:29 UTC 2021
PRIMARY
FDA UNII
21Z359Z1CV
Created by admin on Sat Jun 26 18:11:29 UTC 2021 , Edited by admin on Sat Jun 26 18:11:29 UTC 2021
PRIMARY
INN
11094
Created by admin on Sat Jun 26 18:11:29 UTC 2021 , Edited by admin on Sat Jun 26 18:11:29 UTC 2021
PRIMARY
CAS
2218515-90-1
Created by admin on Sat Jun 26 18:11:29 UTC 2021 , Edited by admin on Sat Jun 26 18:11:29 UTC 2021
PRIMARY
From To
1_22 1_96
1_134 3_214
1_147 1_203
1_226 2_226
1_229 2_229
1_261 1_321
1_367 1_425
1_538 1_637
2_22 2_96
2_134 4_214
2_147 2_203
2_261 2_321
2_367 2_425
2_538 2_637
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL