Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C8H12 |
| Molecular Weight | 108.1809 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C=CC1CCC=CC1
InChI
InChIKey=BBDKZWKEPDTENS-UHFFFAOYSA-N
InChI=1S/C8H12/c1-2-8-6-4-3-5-7-8/h2-4,8H,1,5-7H2
| Molecular Formula | C8H12 |
| Molecular Weight | 108.1809 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Involvement of oxidative stress in 4-vinylcyclohexene-induced toxicity in Drosophila melanogaster. | 2014-06 |
|
| Ovarian expressed microsomal epoxide hydrolase: role in detoxification of 4-vinylcyclohexene diepoxide and regulation by phosphatidylinositol-3 kinase signaling. | 2012-01-01 |
|
| Analysis of acrylonitrile, 1,3-butadiene, and related compounds in acrylonitrile-butadiene-styrene copolymers for kitchen utensils and children's toys by headspace gas chromatography/mass spectrometry. | 2011-02-15 |
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| Adding insult to injury: effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility. | 2010-12 |
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| rac-(1R,2R,4S)-1,2-Dibromo-4-[(1R)-1,2-dibromo-eth-yl]cyclo-hexa-ne. | 2010-11-27 |
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| Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development and VCD-induced ovotoxicity. | 2010-11-15 |
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| Experimental induction of reduced ovarian reserve in a nonhuman primate model (Macaca fascicularis). | 2010-10 |
|
| Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis. | 2010-09-01 |
|
| Dual protective role for glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary. | 2010-09-01 |
|
| Retaining Residual Ovarian Tissue following Ovarian Failure Has Limited Influence on Bone Loss in Aged Mice. | 2010-06-29 |
|
| Formaldehyde in the indoor environment. | 2010-04-14 |
|
| 7,12-dimethylbenz[a]anthracene induces sertoli-leydig-cell tumors in the follicle-depleted ovaries of mice treated with 4-vinylcyclohexene diepoxide. | 2010-02 |
|
| A longitudinal study of the effect of genistein on bone in two different murine models of diminished estrogen-producing capacity. | 2010 |
|
| Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries. | 2009-12-01 |
|
| Using basic science to design a clinical trial: baseline characteristics of women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). | 2009-09 |
|
| Transitional versus surgical menopause in a rodent model: etiology of ovarian hormone loss impacts memory and the acetylcholine system. | 2009-09 |
|
| Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome. | 2009-09 |
|
| Neuroprotection against excitotoxic brain injury in mice after ovarian steroid depletion. | 2009-04-10 |
|
| Ovarian neoplasm development by 7,12-dimethylbenz[a]anthracene (DMBA) in a chemically-induced rat model of ovarian failure. | 2009-03 |
|
| Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes. | 2009-02 |
|
| Steroidogenic capacity of residual ovarian tissue in 4-vinylcyclohexene diepoxide-treated mice. | 2009-02 |
|
| Collaborative work on evaluation of ovarian toxicity. 4) Effects of fertility study of 4-vinylcyclohexene diepoxide in female rats. | 2009 |
|
| Collaborative work on evaluation of ovarian toxicity. 4) Two- or four-week repeated dose study of 4-vinylcyclohexene diepoxide in female rats. | 2009 |
|
| Correlation of serum anti-Müllerian hormone with accelerated follicle loss following 4-vinylcyclohexene diepoxide-induced follicle loss in mice. | 2008-10 |
|
| Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure. | 2008-10 |
|
| Involvement of the KIT/KITL signaling pathway in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in rats. | 2008-08 |
|
| Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice. | 2008-08 |
|
| Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F(1) mice. | 2008-07-01 |
|
| Peer review and reflection continues forever. | 2008-04 |
|
| Development of a sampling and analysis method for 4-vinyl-1-cyclohexene in air. | 2008 |
|
| Effects of impending ovarian failure induced by 4-vinylcyclohexene diepoxide on fertility in C57BL/6 female mice. | 2007-10 |
|
| Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause. | 2007-07 |
|
| Involvement of CYP 2E1 enzyme in ovotoxicity caused by 4-vinylcyclohexene and its metabolites. | 2007-06-01 |
|
| Development of an animal model for ovotoxicity using 4-vinylcyclohexene: a case study. | 2007-04 |
|
| Gold(I)-catalyzed asymmetric cycloisomerization of eneallenes into vinylcyclohexenes. | 2007 |
|
| Ozone's impact on public health: contributions from indoor exposures to ozone and products of ozone-initiated chemistry. | 2006-10 |
|
| Destruction of primordial ovarian follicles in adult cynomolgus macaques after exposure to 4-vinylcyclohexene diepoxide: a nonhuman primate model of the menopausal transition. | 2006-10 |
|
| Dual modality imaging of a novel rat model of ovarian carcinogenesis. | 2006-09-13 |
|
| Effect of bcl-2 overexpression in mice on ovotoxicity caused by 4-vinylcyclohexene. | 2006-08-15 |
|
| Effect of duration of dosing on onset of ovarian failure in a chemical-induced mouse model of perimenopause. | 2006-06-01 |
|
| Recent female mouse models displaying advanced reproductive aging. | 2006-02 |
|
| Characterization of cyclicity and hormonal profile with impending ovarian failure in a novel chemical-induced mouse model of perimenopause. | 2005-12 |
|
| Regioselective alkene carbon-carbon bond cleavage to aldehydes and chemoselective alcohol oxidation of allylic alcohols with hydrogen peroxide catalyzed by [cis-Ru(II)(dmp)2(H2O)2]2+ (dmp = 2,9-dimethylphenanthroline). | 2005-10-27 |
|
| Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause. | 2005-09 |
|
| The three corrugated surfaces of 1,4-divinyltetramethylene diradical intermediates and their connections to 1,2-divinylcyclobutane, 4-vinylcyclohexene, 1,5-cyclooctadiene, and two butadienes. | 2005-04-15 |
|
| Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss. | 2005-03-01 |
|
| Initiation of delayed ovotoxicity by in vitro and in vivo exposures of rat ovaries to 4-vinylcyclohexene diepoxide. | 2004-11 |
|
| 4-Vinyl-1-cyclohexene diepoxide. | 2004 |
|
| 4-Vinyl-1-cyclohexene diepoxide. | 2002 |
|
| Induction of cytochrome P-450 enzymes after repeated exposure to 4-vinylcyclohexene in B6C3F1 mice. | 1999-02 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:34:06 GMT 2025
by
admin
on
Mon Mar 31 21:34:06 GMT 2025
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| Record UNII |
212JQJ15PS
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| Record Status |
Validated (UNII)
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| Record Version |
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| Code System | Code | Type | Description | ||
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100-40-3
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7499
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2872
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C013733
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212JQJ15PS
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DTXSID3021437
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15760
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202-848-9
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4-VINYLCYCLOHEXENE
Created by
admin on Mon Mar 31 21:34:06 GMT 2025 , Edited by admin on Mon Mar 31 21:34:06 GMT 2025
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