INTERSTITIAL COLLAGENASE

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 19:01:54 GMT 2025` Edited by `admin` on `Tue Apr 01 19:01:54 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	20Q1PNI82X
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

INTERSTITIAL COLLAGENASE

Common Name

English

22 KDA INTERSTITIAL COLLAGENASE

Preferred Name

English

MATRIX METALLOPROTEINASE-1

Common Name

English

CLG

Common Name

English

FIBROBLAST COLLAGENASE

Common Name

English

27 KDA INTERSTITIAL COLLAGENASE

Common Name

English

MMP-1

Common Name

English

Classification Tree Code System Code

LOINC

75630-4

Created by admin on Tue Apr 01 19:01:54 GMT 2025 , Edited by admin on Tue Apr 01 19:01:54 GMT 2025

Code System Code Type Description

FDA UNII

20Q1PNI82X

Created by admin on Tue Apr 01 19:01:54 GMT 2025 , Edited by admin on Tue Apr 01 19:01:54 GMT 2025

PRIMARY

From	To
2_9	2_197

Linkage Type	Residue Index
COORDINATION COMPOUND	1_119	1_123	1_129
COORDINATION COMPOUND	1_69	1_71	1_84	1_97

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_21

Related Record Type Details


					BK349F52C9

BATIMASTAT

INHIBITOR -> TARGET

Amount:


					Q0I5D7WT4Q

CL-205241 FREE ACID

INHIBITOR -> TARGET


					80AXY59IT2

CGS-27023

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					W2WJ6ME4K7

UK-370106

NON-INHIBITOR->OFF TARGET

Comments:

20%?inhibition?at?100??M

Qualification:

IC50

Amount:


					F94T42GL80

PG-116800

NON-INHIBITOR->OFF TARGET

Qualification:

IC50

Amount:


					02HQ4TYQ60

CIPEMASTAT

INHIBITOR -> TARGET


					I0403ML141

ILOMASTAT

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					1B47R6ZX4K

REBIMASTAT

INHIBITOR -> TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_119] [1_123] [1_129]	SITE_SPECIFIC	H3-TYPE ZINC FINGER	G6FL3FKF47
AMINO_ACID_SUBSTITUTION	[2_5]	SITE_SPECIFIC	THREONINE PHOSPHATE	3L4WX7B1EI
AMINO_ACID_SUBSTITUTION	[2_91]	SITE_SPECIFIC	TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO_ACID_SUBSTITUTION	[1_69] [1_71] [1_84] [1_97]	SITE_SPECIFIC	UNSPECIFIED SUBSTANCE	fe401322 (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL